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Recombinant human PCBP1 protein

ArtNr NKM-ATGP2314-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSMDAGVTE SGLNVTLTIR LLMHGKEVGS IIGKKGESVK RIREESGARI NISEGNCPER IITLTGPTNA IFKAFAMIID KLEEDINSSM TNSTAASRPP VTLRLVVPAT QCGSLIGKGG CKIKEIREST GAQVQVAGDM LPNSTERAIT IAGVPQSVTE CVKQIC
Citations Beausoleil S.A., et al. (2006) Nat. Biotechnol. 24:1285-1292
Yu L.-R., et al. (2007) J. Proteome Res. 6:4150-4162
NCBI NP_006187
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Poly(rC) binding protein 1,Poly(rC) binding protein 1,hnRNP-E1,hnRNP-X,HNRPE1,HNRPX
Similar products PCBP1, HNRPE1, HNRPX, hnRNP-E1, hnRNP-X, Poly(rC) binding protein 1, ATGP2314-10ug, ATGP2314-20ug, ATGP2314-50ug, ATGP2314-100ug, ATGP2314-250ug, ATGP2314-500ug, ATGP2314-1mg, ATGP2314-10, ATGP2314-20, ATGP2314-50, ATGP2314-100, ATGP2314-250, ATGP2314-500, ATGP2314-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
19.6 kDa (186aa) confirmed by MALDI-TOF
Description
PCBP1 appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC) -binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promotes poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. PCBP1 is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. Recombinant human PCBP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Epigenomics (Transcription & Translation)
Domain
1-163aa
Species of Protein
Human
Manufacturer - Search Terms
PCBP1, Poly(rC) binding protein 1, Poly(rC) binding protein 1, hnRNP-E1, hnRNP-X, HNRPE1, HNRPX, ATGP2314-10ug, ATGP2314-20ug, ATGP2314-50ug, ATGP2314-100ug, ATGP2314-250ug, ATGP2314-500ug, ATGP2314-1mg, ATGP2314-10, ATGP2314-20, ATGP2314-50, ATGP2314-100, ATGP2314-250, ATGP2314-500, ATGP2314-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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