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Recombinant human CRTAP protein

ArtNr NKM-ATGP2548-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 20 ug 4 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSQYERYSF RSFPRDELMP LESAYRHALD KYSGEHWAES VGYLEISLRL HRLLRDSEAF CHRNCSAAPQ PEPAAGLASY PELRLFGGLL RRAHCLKRCK QGLPAFRQSQ PSREVLADFQ RREPYKFLQF AYFKANNLPK AIAAAHTFLL KHPDDEMMKR NMAYYKSLPG AEDYIKDLET KSYESLFIRA VRAYNGENWR TSITDMELAL PD
Citations Tonachini L., et al. (1999) Cytogenet Cell Genet. 87: 191-194.
Castagnola P., et al. (1997) J Cell Sci. 110: 1351-1359.
NCBI NP_006362
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Cartilage-associated protein precursor,Cartilage-associated protein precursor,CASP,LEPREL3,OI7
Similar products CRTAP, CASP, LEPREL3, OI7, Cartilage-associated protein precursor, ATGP2548-10ug, ATGP2548-20ug, ATGP2548-50ug, ATGP2548-100ug, ATGP2548-250ug, ATGP2548-500ug, ATGP2548-1mg, ATGP2548-10, ATGP2548-20, ATGP2548-50, ATGP2548-100, ATGP2548-250, ATGP2548-500, ATGP2548-1
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Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Denatured
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
46.4 kDa (398aa)
Description
Cartilage-associated protein precursor, also known as CRTAP, is a secreted protein localizing to the extracellular space that plays a role in collagen post-translational modifications, extracellular fibril assembly and intracellular trafficking. CRTAP is widely expressed with predominant expression in articular chondrocytes. Mutations in the gene encoding CRTAP can lead to autosomal recessive osteogenesis imperfecta (OI) type 7 and type 2B. OI, also known as brittle bone disease, is characterized by bone fragility and susceptibility to fractures. Recombinant human CRTAP protein, fused to His-tag at N-terminus, was expressed in E. coli.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Antigen Species
Human
Gene Category
Signal Transduction
Domain
27-401aa
Species of Protein
Human
Manufacturer - Search Terms
CRTAP, Cartilage-associated protein precursor, Cartilage-associated protein precursor, CASP, LEPREL3, OI7, ATGP2548-10ug, ATGP2548-20ug, ATGP2548-50ug, ATGP2548-100ug, ATGP2548-250ug, ATGP2548-500ug, ATGP2548-1mg, ATGP2548-10, ATGP2548-20, ATGP2548-50, ATGP2548-100, ATGP2548-250, ATGP2548-500, ATGP2548-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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