Vergleich

Recombinant human CD45 protein

ArtNr NKM-ATGP2577-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 20 ug 4 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGS>VMIA AQGPLKETIG DFWQMIFQRK VKVIVMLTEL KHGDQEICAQ YWGEGKQTYG DIEVDLKDTD KSSTYTLRVF ELRHSKRKDS RTVYQYQYTN WSVEQLPAEP KELISMIQVV KQKLPQKNSS EGNKHHKSTP LLIHCRDGSQ QTGIFCALLN LLESAETEEV VDIFQVVKAL RKARPGMVST FEQYQFLYDV
Citations Charbonneau H., et al. (1988) Proc. Natl. Acad. Sci. u.S.A. 85:7182-7186
Wu L., et al. (2002) Mol. Cell. Biol. 22:2673-2686
NCBI NP_002829.3
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Protein tyrosine phosphatase receptor type isoform 1,Protein tyrosine phosphatase,receptor type,isoform 1,LCA,LY5,B220,CD45,T200,GP180
Similar products CD45, T200, B220, isoform 1, LCA, GP180, receptor type, LY5, Protein tyrosine phosphatase, Protein tyrosine phosphatase receptor type isoform 1, ATGP2577-10ug, ATGP2577-20ug, ATGP2577-50ug, ATGP2577-100ug, ATGP2577-250ug, ATGP2577-500ug, ATGP2577-1mg, ATGP2577-10, ATGP2577-20, ATGP2577-50, ATGP2577-100, ATGP2577-250, ATGP2577-500, ATGP2577-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
29.6 kDa (257aa) confirmed by MALDI-TOF
Description
PTPRC, also known as CD45, is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Recombinant human PTPRC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Stem cell
Domain
1031-1251aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Species of Protein
Human
Manufacturer - Search Terms
CD45, Protein tyrosine phosphatase receptor type isoform 1, Protein tyrosine phosphatase, receptor type, isoform 1, LCA, LY5, B220, CD45, T200, GP180, ATGP2577-10ug, ATGP2577-20ug, ATGP2577-50ug, ATGP2577-100ug, ATGP2577-250ug, ATGP2577-500ug, ATGP2577-1mg, ATGP2577-10, ATGP2577-20, ATGP2577-50, ATGP2577-100, ATGP2577-250, ATGP2577-500, ATGP2577-1

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
lieferbar

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen