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Recombinant human CD40/TNFRSF5 protein

ArtNr NKM-ATGP2615-250ug
Hersteller NKMAX
Menge 250 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGS>EPPTACR EKQYLINSQC CSLCQPGQKL VSDCTEFTET ECLPCGESEF LDTWNRETHC HQHKYCDPNL GLRVQQKGTS ETDTICTCEE GWHCTSEACE SCVLHRSCSP GFGVKQIATG VSDTICEPCP VGFFSNVSSA FEKCHPWTSC ETKDLVVQQA GTNKTDVVCG PQDRLR
Citations Tone M., et al. (2001) Proc. Natl. Acad. Sci. u.S.A. 98:1751-1756
Khandekar S.S., et al. (2001) Protein Expr. Purif. 23:301-310
NCBI NP_001241.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Tumor necrosis factor receptor superfamily member 5,B-cell surface antigen CD40,Bp50,p50,CD40L receptor,CDw40
Similar products CD40, TNFRSF5, Bp50, CDW40, p50, CD40 molecule, TNF receptor superfamily member 5, CD40 molecule TNF receptor superfamily member 5, ATGP2615-10ug, ATGP2615-20ug, ATGP2615-50ug, ATGP2615-100ug, ATGP2615-250ug, ATGP2615-500ug, ATGP2615-1mg, ATGP2615-10, ATGP2615-20, ATGP2615-50, ATGP2615-100, ATGP2615-250, ATGP2615-500, ATGP2615-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
21.6 kDa (196aa) confirmed by MALDI-TOF
Description
CD40 is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Recombinant human CD40 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Stem cell
Domain
21-193aa
Species of Protein
Human
Manufacturer - Search Terms
CD40, TNFRSF5, CD40 molecule TNF receptor superfamily member 5, CD40 molecule, TNF receptor superfamily member 5, Bp50, CDW40, p50, TNFRSF5, ATGP2615-10ug, ATGP2615-20ug, ATGP2615-50ug, ATGP2615-100ug, ATGP2615-250ug, ATGP2615-500ug, ATGP2615-1mg, ATGP2615-10, ATGP2615-20, ATGP2615-50, ATGP2615-100, ATGP2615-250, ATGP2615-500, ATGP2615-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 250 ug
Lieferbar: In stock
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