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Recombinant human TNFR2/TNFRSF1B protein

ArtNr NKM-ATGP3179-250ug
Hersteller NKMAX
Menge 250 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence LPAQVAFTPY APEPGSTCRL REYYDQTAQM CCSKCSPGQH AKVFCTKTSD TVCDSCEDST YTQLWNWVPE CLSCGSRCSS DQVETQACTR EQNRICTCRP GWYCALSKQE GCRLCAPLRK CRPGFGVARP GTETSDVVCK PCAPGTFSNT TSSTDICRPH QICNVVAIPG NASMDAVCTS TSPTRSMAPG AVHLPQPVST RSQHTQPTPE PSTAPSTSFL LPMGPSPPAE GS
Citations Maier O et al., (2013) Biochem. Biophys. Res. Commun. 440(2):336-341.
Govindaraj C et al., (2013) Clin. Immunol. 149(1):97-110.
NCBI NP_001057.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Tumor necrosis factor receptor superfamily member 1B,Tumor necrosis factor receptor 2,TNF-R2,Tumor necrosis factor receptor type II,TNF-RII,TNFR-II,p75,p80 TNF-alpha receptor,Tumor necrosis factor-binding protein 2,TBP-2,TBPII,CD120b,TNFBR,TNFR80,TNF-R75
Similar products TNFRSF1B, p75, TNFR2, CD120b, TNFBR, TBPII, TNF-R-II, TNF-R75, TNFR1B, TNFR80, p75TNFR, TNF RII, ATGP3179-10ug, ATGP3179-20ug, ATGP3179-50ug, ATGP3179-100ug, ATGP3179-250ug, ATGP3179-500ug, ATGP3179-1mg, ATGP3179-10, ATGP3179-20, ATGP3179-50, ATGP3179-100, ATGP3179-250, ATGP3179-500, ATGP3179-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
25.9 kDa (241aa)
Description
TNFRSF1B, also known as tumor necrosis factor receptor superfamily member 1B, mediates most of the metabolic effects of TNF-alpha. The receptor isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. Further, high plasma levels of TNFRSF1B were significantly associated with increased incidence of coronary heart disease. Recombinant human TNFRSF1B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Hormones & Cytokines
Domain
23-257aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by its ability to inhibit cytotoxicity using L-929 mouse fibroblast cells in the presence of Human TNF-α. The ED50 range ≤ 0.2 μg/ml.
Species of Protein
Human
Manufacturer - Search Terms
TNF RII, TNFRSF1B, TNFRSF1B, CD120b, p75, p75TNFR, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, ATGP3179-10ug, ATGP3179-20ug, ATGP3179-50ug, ATGP3179-100ug, ATGP3179-250ug, ATGP3179-500ug, ATGP3179-1mg, ATGP3179-10, ATGP3179-20, ATGP3179-50, ATGP3179-100, ATGP3179-250, ATGP3179-500, ATGP3179-1
Manufacturer - Alternative Names
Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor 2, TNF-R2, Tumor necrosis factor receptor type II, TNF-RII, TNFR-II, p75, p80 TNF-alpha receptor, Tumor necrosis factor-binding protein 2, TBP-2, TBPII, CD120b, TNFBR, TNFR80, TNF-R75

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 250 ug
Lieferbar: In stock
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