Vergleich

Recombinant human CD31/PECAM1 protein

ArtNr NKM-ATGP3214-250ug
Hersteller NKMAX
Menge 250 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence QENSFTINSV DMKSLPDWTV QNGKNLTLQC FADVSTTSHV KPQHQMLFYK DDVLFYNISS MKSTESYFIP EVRIYDSGTY KCTVIVNNKE KTTAEYQVLV EGVPSPRVTL DKKEAIQGGI VRVNCSVPEE KAPIHFTIEK LELNEKMVKL KREKNSRDQN FVILEFPVEE QDRVLSFRCQ ARIISGIHMQ TSESTKSELV TVTESFSTPK FHISPTGMIM EGAQLHIKCT IQ
Citations Brown S., et al. (2002) Nature. 418:200-203.
Dasgupta B., et al. (2009) J Immunol. 182:5041-5051.
NCBI NP_000433
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CD31/EndoCAM,CD31,EndoCAM,GPIIA',PECA1,PECAM1,PECAM-1,Platelet endothelial cell adhesion molecule 1
Similar products PECAM-1, PECAM1, CD31, PECA1, CD31/EndoCAM, GPIIA', endoCAM, ATGP3214-10ug, ATGP3214-20ug, ATGP3214-50ug, ATGP3214-100ug, ATGP3214-250ug, ATGP3214-500ug, ATGP3214-1mg, ATGP3214-10, ATGP3214-20, ATGP3214-50, ATGP3214-100, ATGP3214-250, ATGP3214-500, ATGP3214-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
65.5 kDa (582aa)
Description
PECAM1, also known as platelet endothelial cell adhesion molecule, induces susceptibility to atherosclerosis. It prevents phagocyte ingestion of closely apposed viable cells by transmitting detachment signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes. The encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. Recombinant human PECAM1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Cardiovascular
Domain
28-601aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by the ability of the immobilized protein to support the adhesion of Jurkat human acute T cell leukemia cells. When cells are added to human CD31 coated plates 5 ug/ml. This effect is more to 40%.
Species of Protein
Human
Manufacturer - Search Terms
CD31, PECAM1, PECAM1, CD31, CD31/EndoCAM, endoCAM, GPIIA', PECA1, PECAM-1, ATGP3214-10ug, ATGP3214-20ug, ATGP3214-50ug, ATGP3214-100ug, ATGP3214-250ug, ATGP3214-500ug, ATGP3214-1mg, ATGP3214-10, ATGP3214-20, ATGP3214-50, ATGP3214-100, ATGP3214-250, ATGP3214-500, ATGP3214-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 250 ug
Lieferbar: In stock
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