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Recombinant human GSK-3 beta protein

ArtNr NKM-ATGP3221-250ug
Hersteller NKMAX
Menge 250 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence MSGRPRTTSF AESCKPVQQP SAFGSMKVSR DKDGSKVTTV VATPGQGPDR PQEVSYTDTK VIGNGSFGVV YQAKLCDSGE LVAIKKVLQD KRFKNRELQI MRKLDHCNIV RLRYFFYSSG EKKDEVYLNL VLDYVPETVY RVARHYSRAK QTLPVIYVKL YMYQLFRSLA YIHSFGICHR DIKPQNLLLD PDTAVLKLCD FGSAKQLVRG EPNVSYICSR YYRAPELIFG AT
Citations Desai SS., et al. (2014) J. Biol. Chem. 289(9):5386-5398.
Cheng DD., et al. (2014) Biochem. Biophys. Res. Commun. 443(2):598-603.
Jung SH, et al. Identification of transglutaminase 2 kinase substrates using a novel on-chip activity assay. (Biosens Bioelectron. 2016){https://pubmed.ncbi.nlm.nih.gov/27040940/}
Jung SH, et al. Systematic investigation of protein kinase A substrate proteins using on-chip protein kinase kinetic profiling. (Analyst. 2017){https://pubmed.ncbi.nlm.nih.gov/28536714/}
NCBI NP_001139628.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias GSK-3 beta,Serine/threonine-protein kinase GSK3B
Similar products Serine/threonine-protein kinase GSK3B, GSK-3 beta, GSK3 b, ATGP3221-10ug, ATGP3221-20ug, ATGP3221-50ug, ATGP3221-100ug, ATGP3221-250ug, ATGP3221-500ug, ATGP3221-1mg, ATGP3221-10, ATGP3221-20, ATGP3221-50, ATGP3221-100, ATGP3221-250, ATGP3221-500, ATGP3221-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
47.5 kDa (426aa)
Description
GSK3B, also known as glycogen synthase kinase-3 beta, acts as a negative regulator in the hormonal control of glucose homeostasis. Also, this protein has diverse functions as Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. Recombinant human GSK3B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 0.5mM PMSFand 30% glycerol
Antigen Species
Human
Gene Category
Neuroscience
Domain
1-420aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Species of Protein
Human
Manufacturer - Search Terms
GSK3 b, GSK-3 beta, Serine/threonine-protein kinase GSK3B, ATGP3221-10ug, ATGP3221-20ug, ATGP3221-50ug, ATGP3221-100ug, ATGP3221-250ug, ATGP3221-500ug, ATGP3221-1mg, ATGP3221-10, ATGP3221-20, ATGP3221-50, ATGP3221-100, ATGP3221-250, ATGP3221-500, ATGP3221-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 250 ug
Lieferbar: In stock
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