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Recombinant mouse Legumain/Asparaginyl Endopeptidase protein

ArtNr NKM-ATGP3295-50ug
Hersteller NKMAX
Menge 50 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Mouse (Murine, Mus musculus)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence VPVGVDDPED GGKHWVVIVA GSNGWYNYRH QADACHAYQI IHRNGIPDEQ IIVMMYDDIA NSEENPTPGV VINRPNGTDV YKGVLKDYTG EDVTPENFLA VLRGDAEAVK GKGSGKVLKS GPRDHVFIYF TDHGATGILV FPNDDLHVKD LNKTIRYMYE HKMYQKMVFY IEACESGSMM NHLPDDINVY ATTAANPKES SYACYYDEER GTYLGDWYSV NWMEDSDVED LT
Citations Shirahama-Noda K., et al. (2003) J. Biol. Chem. 278:33194-33199.
Liu C., et al. (2003) Cancer Res. 63:2957-2964.
NCBI NP_035305
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Legumain,AEP,AI746452,AU022324,Prsc1
Similar products Legumain, AEP, Asparaginyl Endopeptidase, Prsc1, AI746452, AU022324, ATGP3295-10ug, ATGP3295-20ug, ATGP3295-50ug, ATGP3295-100ug, ATGP3295-250ug, ATGP3295-500ug, ATGP3295-1mg, ATGP3295-10, ATGP3295-20, ATGP3295-50, ATGP3295-100, ATGP3295-250, ATGP3295-500, ATGP3295-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
48.6 kDa (426aa)
Description
LGMN, also known as legumain, is a lysosomal cysteine protease found in all mouse tissues, but was particularly abundant in kidney and placenta. It plays a pivotal role in the endosomal/lysosomal degradation system because the Legumain deficiency causes the accumulation of pro cathepsins B, H and L, another group of lysosomal cysteine proteases. Over expression of Legumain in tumors is significant for invasion/metastasis. Recombinant mouse LGMN, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Mouse
Gene Category
Immunology
Domain
18-435aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Predicted nterm
Val18
Species of Protein
Mouse
Manufacturer - Search Terms
Legumain, Asparaginyl Endopeptidase, Legumain, AEP, AI746452, AU022324, Prsc1, ATGP3295-10ug, ATGP3295-20ug, ATGP3295-50ug, ATGP3295-100ug, ATGP3295-250ug, ATGP3295-500ug, ATGP3295-1mg, ATGP3295-10, ATGP3295-20, ATGP3295-50, ATGP3295-100, ATGP3295-250, ATGP3295-500, ATGP3295-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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