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Recombinant rat Lactate Dehydrogenase A/LDHA protein

Recombinant rat Lactate Dehydrogenase A/LDHA protein

ArtNr	NKM-ATGP3368-50ug
Hersteller	NKMAX
Menge	50 ug
Quantity options	10 ug 50 ug
Kategorie	Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Toxicity & Cytotoxicity
Typ	Proteins Recombinant
Format	Liquid
Applikationen	SDS-PAGE
Specific against	Rat (Rattus norvegicus)
Host	Baculovirus-Infected Insect Cells
Konjugat/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	MAALKDQLIV NLLKEEQVPQ NKITVVGVGA VGMACAISIL MKDLADELAL VDVIEDKLKG EMMDLQHGSL FLKTPKIVSS KDYSVTANSK LVIITAGARQ QEGESRLNLV QRNVNIFKFI IPNVVKYSPQ CKLLIVSNPV DILTYVAWKI SGFPKNRVIG SGCNLDSARF RYLMGERLGV HPLSCHGWVL GEHGDSSVPV WSGVNVAGVS LKSLNPQLGT DADKEQWKDV HK
Citations	Ward RA., et al. (2012) J Med Chem. 55:3285-3306. Fantin VR., et al. (2006) Cancer Cell. 9:425-434.
NCBI	NP_058721
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	LDH muscle subunit,LDH-M
Similar products	LDHA, Ldha, L-lactate dehydrogenase A chain, Lactate Dehydrogenase A, Ldh1, ATGP3368-10ug, ATGP3368-20ug, ATGP3368-50ug, ATGP3368-100ug, ATGP3368-250ug, ATGP3368-500ug, ATGP3368-1mg, ATGP3368-10, ATGP3368-20, ATGP3368-50, ATGP3368-100, ATGP3368-250, ATGP3368-500, ATGP3368-1
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Manufacturer - Type	Recombinant Protein
Manufacturer - Applications	SDS-PAGE, Enzyme Activity
Manufacturer - Host	Baculovirus
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	37.5 kDa (340aa)
Description	Ldha, also known as lactate dehydrogenase A, catalyzes the conversion of pyruvate to lactate, utilizing NADH as a cofactor. It has been identified as a potential therapeutic target in the area of cancer metabolism. Reduction in Ldha activity resulted in stimulation of mitochondrial respiration and decrease of mitochondrial membrane potential. Recombinant rat Ldha, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration	0.25mg/ml (determined by absorbance at 280nm)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 1mM DTT, 20% glycerol
Antigen Species	Rat
Gene Category	Signal Transduction
Domain	1-332aa
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only	Specific activity is > 200unit/mg, in which one unit will convert 1.0 umole of pyruvate to L-lactate and beta-NAD per minute at pH 7.5 at 37C.
Predicted nterm	Met1
Species of Protein	Rat
Manufacturer - Search Terms	Lactate Dehydrogenase A, LDHA, L-lactate dehydrogenase A chain, Ldha, Ldh1, ATGP3368-10ug, ATGP3368-20ug, ATGP3368-50ug, ATGP3368-100ug, ATGP3368-250ug, ATGP3368-500ug, ATGP3368-1mg, ATGP3368-10, ATGP3368-20, ATGP3368-50, ATGP3368-100, ATGP3368-250, ATGP3368-500, ATGP3368-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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NKM-ATGP3368-50ug-datasheet.pdf

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Menge: 50 ug

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Lieferung vsl. bis 04.09.2025

Express-Lieferung: 29 Tage sparen

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