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Recombinant human LTA/TNF-beta protein

ArtNr NKM-ATGP3420-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug 5 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADP>LPGVGLT PSAAQTARQH PKMHLAHSTL KPAAHLIGDP SKQNSLLWRA NTDRAFLQDG FSLSNNSLLV PTSGIYFVYS QVVFSGKAYS PKATSSPLYL AHEVQLFSSQ YPFHVPLLSS QKMVYPGLQE PWLHSMYHGA AFQLTQGDQL STHTDGIPHL VLSPSTVFFG AFAL<HHHHHH>
Citations Messer G., et al. (1991) J Exp Med. 173:209-219.
Gramaglia I., et al. (1999) J Immunol 162:1333-1338
NCBI NP_001153212
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Lymphotoxin-alpha,LT-alpha,TNF-beta,Tumor necrosis factor ligand superfamily member 1,TNFB,TNFSF1,TNF superfamily,member 1
Similar products TNF-beta, LTA, TNF-b, TNF B, Lymphotoxin-alpha, LT-alpha, Tumor necrosis factor ligand superfamily member 1, TNFB, TNFSF1, TNFbeta, LT, Lta, DIF, LT alpha, LTalpha, Lymphotoxin alpha, Lymphotoxin alpha (TNF superfamily, member 1), TNF superfamily member 1, TNFB_HUMAN, Tumor necrosis factor beta, TNLG1E, Lymphotoxin-a, ATGP3420-10ug, ATGP3420-20ug, ATGP3420-50ug, ATGP3420-100ug, ATGP3420-250ug, ATGP3420-500ug, ATGP3420-1mg, ATGP3420-10, ATGP3420-20, ATGP3420-50, ATGP3420-100, ATGP3420-250, ATGP3420-500, ATGP3420-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
19.7 kDa (180aa)
Description
LTA, also known as lymphotoxin alpha and tumor necrosis factor beta, belongs to the tumor necrosis factor family. It is highly inducible, secreted, and forms heterotrimers with lymphotoxin beta which anchor lymphotoxin alpha to the cell surface. It is expressed by activated naive CD4 cells, unpolarized IL2 secreting effectors, and Th1 effectors and mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. Recombinant human LTA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques
Concentration
0.5mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Immunology
Domain
35-205aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured in a cytotoxicity assay using L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 range ≤ 1ng/ml.
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
Lymphotoxin-a , TNF-b, Lymphotoxin alpha, LTA, LT, TNFB, TNFSF1, TNLG1E, LTalpha, DIF, LT, LT alpha, LT-alpha, Lta, Lymphotoxin alpha, Lymphotoxin alpha (TNF superfamily, member 1), Lymphotoxin-alpha, TNF B, TNF superfamily member 1, TNF-beta, TNFB, TNFB_HUMAN, TNFbeta, TNFSF1, Tumor necrosis factor beta, Tumor necrosis factor ligand superfamily member 1, ATGP3420-10ug, ATGP3420-20ug, ATGP3420-50ug, ATGP3420-100ug, ATGP3420-250ug, ATGP3420-500ug, ATGP3420-1mg, ATGP3420-10, ATGP3420-20, ATGP3420-50, ATGP3420-100, ATGP3420-250, ATGP3420-500, ATGP3420-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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