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Recombinant human PD-1 protein

ArtNr NKM-ATGP3612-50ug
Hersteller NKMAX
Menge 50 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADP>PGWFLDS PDRPWNPPTF SPALLVVTEG DNATFTCSFS NTSESFVLNW YRMSPSNQTD KLAAFPEDRS QPGQDCRFRV TQLPNGRDFH MSVVRARRND SGTYLCGAIS LAPKAQIKES LRAELRVTER RAEVPTAHPS PSPRPAGQFQ TLV<LEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP
Citations Ishida Y., et al, (1992) EMBO J. 11:3887-3895.
Lastwika KJ., et al, (2016) Cancer Res. 76:227-238.
NCBI NP_005009.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Programmed cell death protein 1,PDCD1,CD279,hPD-1,hPD-l,hSLE1,PD-1,PD1,SLEB2
Lieferbar
Manufacturer - Type
Proteins
Manufacturer - Category
Recombinant Protein
Manufacturer - Conjugate / Tag
hIgG-His-Tag
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
44 kDa (392aa)
Description
PDCD1, also known as programmed cell death protein 1, is a type 1 transmembrane glycoprotein, and is an immune-receptor belonging to the CD28/CTLA4 family. This protein is expressed on the surface of activated T-cell, B-cell, macrophages, myeloid cells and subset of thymocytes. Also, it inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4 and IL-10. As a cell surface molecule, it regulates the adaptive immune response. Recombinant human PDCD1, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Apoptosis
Domain
21-170aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
PD1, Programmed cell death protein 1, PDCD1, CD279, hPD-1, hPD-l, hSLE1, PD-1, PD1, SLEB2, PD-1, PD1 protein, ATGP3612-10ug, ATGP3612-20ug, ATGP3612-50ug, ATGP3612-100ug, ATGP3612-250ug, ATGP3612-500ug, ATGP3612-1mg, ATGP3612-10, ATGP3612-20, ATGP3612-50, ATGP3612-100, ATGP3612-250, ATGP3612-500, ATGP3612-1
Manufacturer - Similar Names
PD1, Programmed cell death protein 1, PDCD1, CD279, hPD-1, hPD-l, hSLE1, PD-1, PD1, SLEB2, PD-1, PD1 protein, ATGP3612-10ug, ATGP3612-20ug, ATGP3612-50ug, ATGP3612-100ug, ATGP3612-250ug, ATGP3612-500ug, ATGP3612-1mg, ATGP3612-10, ATGP3612-20, ATGP3612-50, ATGP3612-100, ATGP3612-250, ATGP3612-500, ATGP3612-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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