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Recombinant human PD-L1/B7-H1 protein

ArtNr NKM-ATGP3631-250ug
Hersteller NKMAX
Menge 250 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <ADL>FTVTVPK DLYVVEYGSN MTIECKFPVE KQLDLAALIV YWEMEDKNII QFVHGEEDLK VQHSSYRQRA RLLKDQLSLG NAALQITDVK LQDAGVYRCM ISYGGADYKR ITVKVNAPYN KINQRILVVD PVTSEHELTC QAEGYPKAEV IWTSSDHQVL SGKTTTTNSK REEKLFNVTS TLRINTTTNE IFYCTFRRLD PEENHTAELV IPELPLAHPP NER<LEPKSCD
Citations Dong H., et al, (1999) Nat. Med. 5:1365-1369.
Trabattoni D., et al, (2003) Blood 101:2514-2520.
NCBI NP_054862.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Programmed cell death 1 ligand 1 isoform,CD274,B7-H,B7H1,PD-L1,PDCD1L1,PDCD1LG1,PDL1
Lieferbar
Manufacturer - Type
Proteins
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Category
Recombinant Protein
Manufacturer - Conjugate / Tag
hIgG-His-Tag
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
52.5 kDa (462aa)
Description
CD274, also known as programmed cell death 1 ligand 1 isoform, is a member of the growing B7 family of immune molecules. This protein is involved in the regulation of cellular and humoral immune responses. It suppresses T cell activation and proliferation and induces the apoptosis of activated T cells. Also, it plays a role in the development of immune tolerance by promoting T cell anergy and enhancing regulatory T cell development. Recombinant human CD274, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Immunology
Domain
19-238aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by its binding ability in a functional ELISA with Human PD-1 (CAT# ATGP4027). The ED50 range ≤ 0.5 ug/ml.
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
PD-L1, B7-H1, Programmed cell death 1 ligand 1 isoform, CD274, B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, ATGP3631-10ug, ATGP3631-20ug, ATGP3631-50ug, ATGP3631-100ug, ATGP3631-250ug, ATGP3631-500ug, ATGP3631-1mg, ATGP3631-10, ATGP3631-20, ATGP3631-50, ATGP3631-100, ATGP3631-250, ATGP3631-500, ATGP3631-1
Manufacturer - Similar Names
PD-L1, B7-H1, Programmed cell death 1 ligand 1 isoform, CD274, B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, ATGP3631-10ug, ATGP3631-20ug, ATGP3631-50ug, ATGP3631-100ug, ATGP3631-250ug, ATGP3631-500ug, ATGP3631-1mg, ATGP3631-10, ATGP3631-20, ATGP3631-50, ATGP3631-100, ATGP3631-250, ATGP3631-500, ATGP3631-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 250 ug
Lieferbar: In stock
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