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Recombinant rat IL-6 protein

ArtNr NKM-ATGP3711-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 20 ug 5 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Rat (Rattus norvegicus)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <ADP>FPTSQVR RGDFTEDTTH NRPVYTTSQV GGLITYVLRE ILEMRKELCN GNSDCMNSDDALSENNLKLP EIQRNDGCFQ TGYNQEICLL KICSGLLEFR FYLEFVKNNL QDNKKDKARVIQSNTETLVH IFKQEIKDSY KIVLPTPTSN ALLMEKLESQ KEWLRTKTIQ LILKALEEFL KVTMRSTRQT <HHHHHH>
Citations Garbers C., et al, (2012) Cytokine Growth Factor Rev. 23:85-97.
Northemann W., et al, (1989) J. Biol. Chem. 264:16072-16082.
NCBI NP_036721
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Interleukin 6,Il6,Ifnb2,ILg6,Interferon beta 2
Similar products IL6, ATGP3711-10ug, ATGP3711-20ug, ATGP3711-50ug, ATGP3711-100ug, ATGP3711-250ug, ATGP3711-500ug, ATGP3711-1mg, ATGP3711-10, ATGP3711-20, ATGP3711-50, ATGP3711-100, ATGP3711-250, ATGP3711-500, ATGP3711-1
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Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
22.8 kDa (196aa)
Description
Il6, also known as interleukin 6, is an alpha-helical phosphorylated and glycosylated cytokine. This protein is important roles in the acute phase reaction, inflammation, hematopoiesis, bone metabolism and cancer progression. Also, it can function as an anti-inflammatory molecule, as in skeletal muscle where it is secreted in response to exercise In addition, it enhances hematopoietic stem cell proliferation and the differentiation of Th17 cells, memory B cells, and plasma cells. Recombinant rat Il6, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol
Antigen Species
Rat
Gene Category
Hormones & Cytokines
Domain
25-211aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured in a cell proliferation assay using M-NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 range ≤0.1ng/ml.
Predicted nterm
Ala
Species of Protein
Rat
Manufacturer - Search Terms
IL6, ATGP3711-10ug, ATGP3711-20ug, ATGP3711-50ug, ATGP3711-100ug, ATGP3711-250ug, ATGP3711-500ug, ATGP3711-1mg, ATGP3711-10, ATGP3711-20, ATGP3711-50, ATGP3711-100, ATGP3711-250, ATGP3711-500, ATGP3711-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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