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Recombinant human CD3 zeta/CD247 protein

ArtNr NKM-ATGP3754-20ug
Hersteller NKMAX
Menge 20 ug
Quantity options 100 ug 20 ug 4 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADP>RVKFSRS ADAPAYQQGQ NQLYNELNLG RREEYDVLDK RRGRDPEMGG KPQRRKNPQE GLYNELQKDK MAEAYSEIGM KGERRRGKGH DGLYQGLSTA TKDTYDALHM QALPPR<HHHH HH>
Citations Tomita K., et al. (2001) J. Biol. Chem. 276:25378-25385.
Li R., et al. (2012) Lupus. 21:75-83.
NCBI NP_932170.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias TCRZ,T-cell surface glycoprotein CD3 zeta chain isoform 1,T3Z,IMD25,CD3-ZETA,CD3Z,CD3Q,CD3H,CD247
Lieferbar
Manufacturer - Type
Proteins
Manufacturer - Category
Recombinant Protein
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
14.1 kDa (122aa)
Description
CD247, also known as T-cell surface glycoprotein CD3 zeta chain isoform 1, belongs to CD3Z / FCER1G family. The T cell receptor Zeta together, with alpha / beta and gamma / delta heterodimers. This Protein plays an important role in binding antigen recognition to multiple intracellular signaling pathways and also plays a role in assembly and expression of the TCR complex. Defects in CD247 defects can cause immune deficiencies. Immune deficiency, characterized by T cells, impaired immune responses to allogeneic antigens, tetanus toxoid and mitogen. Recombinant human CD247, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.2mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 6.8) containing 50% glycerol, 1mM DTT, 1mM EDTA, 0.1M NaCl
Antigen Species
Human
Gene Category
Immunology
Domain
52-164aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
TCRZ, T-cell surface glycoprotein CD3 zeta chain isoform 1, T3Z, IMD25, CD3-ZETA, CD3Z, CD3Q, CD3H, CD247, ATGP3754-10ug, ATGP3754-20ug, ATGP3754-50ug, ATGP3754-100ug, ATGP3754-250ug, ATGP3754-500ug, ATGP3754-1mg, ATGP3754-010, ATGP3754-020, ATGP3754-050, ATGP3754-100, ATGP3754-250, ATGP3754-500, ATGP3754-01M
Manufacturer - Similar Names
TCRZ, T-cell surface glycoprotein CD3 zeta chain isoform 1, T3Z, IMD25, CD3-ZETA, CD3Z, CD3Q, CD3H, CD247, ATGP3754-10ug, ATGP3754-20ug, ATGP3754-50ug, ATGP3754-100ug, ATGP3754-250ug, ATGP3754-500ug, ATGP3754-1mg, ATGP3754-010, ATGP3754-020, ATGP3754-050, ATGP3754-100, ATGP3754-250, ATGP3754-500, ATGP3754-01M

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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