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Recombinant human HLA-DRB1 protein

ArtNr NKM-ATGP3818-10ug
Hersteller NKMAX
Menge 10 ug
Quantity options 10 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence ADPGDTRPRF LWQPKRECHF FNGTERVRFL DRYFYNQEES VRFDSDVGEF RAVTELGRPD AEYWNSQKDI LEQARAAVDT YCRHNYGVVE SFTVQRRVQP KVTVYPSKTQ PLQHHNLLVC SVSGFYPGSI EVRWFLNGQE EKAGMVSTGL IQNGDWTFQT LVMLETVPRS GEVYTCQVEH PSVTSPLTVE WRARSESAQS KHHHHHH
Citations De Silvestri A., et al. (2017) Autoimmun Rev. 16:1230-1236.
Riberdy JM., et al. (1992) Nature. 360:474-477.
NCBI NP_002115
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Major histocompatibility complex,class II,DR beta 1,HLA-DRB1,DRB1,HLA-DR1B,HLA-DRB,SS1
Lieferbar
Manufacturer - Type
Proteins
Manufacturer - Category
Recombinant Protein
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
24 kDa (207aa)
Description
HLA-DRB1, also known as major histocompatibility complex, class II, DR beta 1 precursor, belongs to the human leukocyte antigen (HLA) class II beta chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins to T helper cells. It helps the immune system distinguish the body's own proteins from proteins made by foreign invaders such as viruses and bacteria. It is associated with an increased incidence of rheumatoid arthritis. Recombinant human HLA-DRB1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol
Antigen Species
Human
Gene Category
Immunology
Domain
30-227aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
HLA-DRB1, Major histocompatibility complex, class II, DR beta 1, HLA-DRB1, DRB1, HLA-DR1B, HLA-DRB, SS1, ATGP3818-10ug, ATGP3818-20ug, ATGP3818-50ug, ATGP3818-100ug, ATGP3818-250ug, ATGP3818-500ug, ATGP3818-1mg, ATGP3818-10, ATGP3818-20, ATGP3818-50, ATGP3818-100, ATGP3818-250, ATGP3818-500, ATGP3818-1
Manufacturer - Similar Names
HLA-DRB1, Major histocompatibility complex, class II, DR beta 1, HLA-DRB1, DRB1, HLA-DR1B, HLA-DRB, SS1, ATGP3818-10ug, ATGP3818-20ug, ATGP3818-50ug, ATGP3818-100ug, ATGP3818-250ug, ATGP3818-500ug, ATGP3818-1mg, ATGP3818-10, ATGP3818-20, ATGP3818-50, ATGP3818-100, ATGP3818-250, ATGP3818-500, ATGP3818-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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