Recombinant human EphB4 protein

Recombinant Protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

EPHB4, also known ephrin type-B receptor 4, is a member of the Eph receptor tyrosine kinase family. It binds transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. This protein plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. And the signaling of this protein controls cellular repulsion and segregation form EFNB2-expressing cells. And it also plays a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis. Recombinant human EPHB4 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cardiovascular

< 1 EU per 1ug of protein (determined by LAL method)

Human

EPHB4, Ephrin type-B receptor 4, EPHB4, HFASD, HTK, MYK1, TYRO11, ATGP3843-10ug, ATGP3843-20ug, ATGP3843-50ug, ATGP3843-100ug, ATGP3843-250ug, ATGP3843-500ug, ATGP3843-1mg, ATGP3843-10, ATGP3843-20, ATGP3843-50, ATGP3843-100, ATGP3843-250, ATGP3843-500, ATGP3843-1