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Recombinant human Angiopoietin 2/ANGPT2 protein

ArtNr NKM-ATGP3853-50ug
Hersteller NKMAX
Menge 50 ug
Quantity options 100 ug 20 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host CHO cells
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence YNNFRKSMDS IGKKQYQVQH GSCSYTFLLP EMDNCRSSSS PYVSNAVQRD APLEYDDSVQ RLQVLENIME NNTQWLMKLE NYIQDNMKKEMVEIQQNAVQ NQTAVMIEIG TNLLNQTAEQ TRKLTDVEAQ VLNQTTRLEL QLLEHSLSTN KLEKQILDQT SEINKLQDKN SFLEKKVLAMEDKHIIQLQS IKEEKDQLQV LVSKQNSIIE ELEKKIVTAT VNNSVLQKQQ HDLM
Citations Maisonpierre PC., et al. (1997) Science. 277:55-60.
Nowicki M., et al. (2017) Ann Hematol. 96:2103-2112.
NCBI NP_001138
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Angiopoietin-2 isoform a,ANGPT2,AGPT2,ANG2
Similar products Angiopoietin2, ATGP3853-10ug, ATGP3853-20ug, ATGP3853-50ug, ATGP3853-100ug, ATGP3853-250ug, ATGP3853-500ug, ATGP3853-1mg, ATGP3853-10, ATGP3853-20, ATGP3853-50, ATGP3853-100, ATGP3853-250, ATGP3853-500, ATGP3853-1
Lieferbar
Manufacturer - Type
Proteins
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Category
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
55.7 kDa (484aa)
Description
Angiopoietin-2, also known as ANGPT2, is a member of the ANG family. It has been identified as ligands for vascular endothelial-specific Tie2 receptor tyrosine kinase that interact with ANG2. This protein may be important growth factors in the generation of new blood vessels. Also, it is over-expression disrupts blood vessel formation in the mouse embryo. This protein is strongly expressed only at sites of vascular remodeling. It has been suggested that it may act synergistically with other cytokines such as vascular endothelial growth factor to promote tumor-associated Angiogenesis and tumor progression. Recombinant human Angiopoietin-2 fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Angiogenesis
Domain
19-496aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured by its binding ability in a functional ELISA with Human TIE-2 (CAT# ATGP3947)
Predicted nterm
Tyr19
Species of Protein
Human
Manufacturer - Search Terms
Angiopoietin2, ATGP3853-10ug, ATGP3853-20ug, ATGP3853-50ug, ATGP3853-100ug, ATGP3853-250ug, ATGP3853-500ug, ATGP3853-1mg, ATGP3853-10, ATGP3853-20, ATGP3853-50, ATGP3853-100, ATGP3853-250, ATGP3853-500, ATGP3853-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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