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Recombinant human Carboxylesterase 1/CES1 protein

ArtNr NKM-ATGP3862-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 10 ug 200 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence ADLGHPSSPP VVDTVHGKVL GKFVSLEGFA QPVAIFLGIP FAKPPLGPLR FTPPQPAEPW SFVKNATSYP PMCTQDPKAG QLLSELFTNR KENIPLKLSE DCLYLNIYTP ADLTKKNRLP VMVWIHGGGL MVGAASTYDG LALAAHENVV VVTIQYRLGI WGFFSTGDEH SRGNWGHLDQ VAALRWVQDN IASFGGNPGS VTIFGESAGG ESVSVLVLSP LAKNLFHRAI SE
Citations Satoh T., et al, (2006) Chem Biol Interact. 162:195-211.
Redinbo MR., et al. (2005) Drug Discovery Today 10:313.
NCBI NP_001020366
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Liver carboxylesterase 1 isoform a,CES1,ACAT,CE-1,CEH,CES2,hCE-1,HMSE,HMSE1,PCE-1,REH,SES1,TGH
Similar products CES1, CES2, SES1, ACAT, CEH, HMSE, HMSE1, PCE-1, TGH, REH, CE-1, hCE-1, Carboxylesterase1, Carboxylesterase 1/CES1Liver carboxylesterase 1 isoform a, ATGP3862-10ug, ATGP3862-20ug, ATGP3862-50ug, ATGP3862-100ug, ATGP3862-250ug, ATGP3862-500ug, ATGP3862-1mg, ATGP3862-10, ATGP3862-20, ATGP3862-50, ATGP3862-100, ATGP3862-250, ATGP3862-500, ATGP3862-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
Enzyme Activity, SDS-PAGE
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
61.7 kDa (559aa)
Description
Carboxylesterase 1, also known as liver carboxylesterase 1 isoform a, is a member of a large family of carboxylesterases. It is also part of the alpha/beta fold hydrolase family. Carboxylesterases hydrolyze long-chain fatty acid esters and thioesters. The resulting carboxylates are then often conjugated by other enzymes to increase solubility and eventually excreted. Also, this enzyme may play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. This protein is known to react aromatic and aliphatic esters and can manage cellular cholesterol esterification levels. It is present in most tissues with higher levels in the liver and low levels in the gastrointestinal tract. Recombinant human Carboxylesterase 1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. 25mM Sodium Acetate (pH 4.0) containing 10% glycerol, 0.1M NaCl, 0.1mM PMSF
Antigen Species
Human
Gene Category
Cardiovascular
Domain
19-568aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Specific activity is > 700pmol/min/ug and is defined as the amount of enzyme that hydrolyze 1pmole of p-nitrophenyl acetate to pnitrophenol per minute at pH 7.5 at 37C.
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
Carboxylesterase1, CES1, Carboxylesterase 1/CES1Liver carboxylesterase 1 isoform a, CES1, ACAT, CE-1, CEH, CES2, hCE-1, HMSE, HMSE1, PCE-1, REH, SES1, TGH, ATGP3862-10ug, ATGP3862-20ug, ATGP3862-50ug, ATGP3862-100ug, ATGP3862-250ug, ATGP3862-500ug, ATGP3862-1mg, ATGP3862-10, ATGP3862-20, ATGP3862-50, ATGP3862-100, ATGP3862-250, ATGP3862-500, ATGP3862-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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