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Recombinant human CTHRC1 protein

ArtNr NKM-ATGP3863-50ug
Hersteller NKMAX
Menge 50 ug
Quantity options 100 ug 10 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host Baculovirus-Infected Insect Cells
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <ADP>SEIPKGK QKAQLRQREV VDLYNGMCLQ GPAGVPGRDG SPGANGIPGT PGIPGRDGFK GEKGECLRES FEESWTPNYK QCSWSSLNYG IDLGKIAECT FTKMRSNSAL RVLFSGSLRL KCRNACCQRW YFTFNGAECS GPLPIEAIIY LDQGSPEMNS TINIHRTSSV EGLCEGIGAG LVDVAIWVGT CSDYPKGDAS TGWNSVSRII IEELPK<HHHH HH>
Citations Jin YR., et al. (2017) Bone. 97:153-167.
He W., et al. (2018) BMC Cancer. 18:400. doi
NCBI NP_612464
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Collagen triple helix repeat-containing protein 1 isoform 1,CTHRC1,Protein NMTC1
Similar products CTHRC1, ATGP3863-10ug, ATGP3863-20ug, ATGP3863-50ug, ATGP3863-100ug, ATGP3863-250ug, ATGP3863-500ug, ATGP3863-1mg, ATGP3863-10, ATGP3863-20, ATGP3863-50, ATGP3863-100, ATGP3863-250, ATGP3863-500, ATGP3863-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Host
Baculovirus
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
24.1 kDa (222aa)
Description
CTHRC1, also known as collagen triple helix repeat-containing protein 1 isoform 1, is a secreted glycoprotein that is expressed on renal epithelium, neurons, osteoblasts, and smooth muscle cells. This protein is overexpressed in different kinds of cancer tissues and promotes tumor formation. It acts as a negative regulator of collagen matrix deposition and is involved in cell migration, motility and invasion. The hormonal functions of CTHRC1 include regulation of lipid storage and cellular glycogen levels with potentially far-reaching implications for cell metabolism and physiology. Additionally, CTHRC1 increases bone mass as a positive regulator of osteoblastic bone formation and offers an anabolic approach for the treatment of osteoporosis. Recombinant human CTHRC1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by absorbance at 280nm)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Cytoskeleton
Domain
31-243aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Predicted nterm
Ala
Species of Protein
Human
Manufacturer - Search Terms
CTHRC1, ATGP3863-10ug, ATGP3863-20ug, ATGP3863-50ug, ATGP3863-100ug, ATGP3863-250ug, ATGP3863-500ug, ATGP3863-1mg, ATGP3863-10, ATGP3863-20, ATGP3863-50, ATGP3863-100, ATGP3863-250, ATGP3863-500, ATGP3863-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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Lieferung vsl. bis 31.07.2025 

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