Recombinant human CD21 protein

Recombinant Protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

CD21, also known as complement receptor type 2 isoform 2, is an N-glycosylated member of the regulators of complement activation family of proteins. This protein is present on all mature B-cells and some T-cells and follicular dendritic cells and is released by proteolytic shedding from activated B cell. It forms a complex with the B cell receptor-associated CD19 molecule and lowers the threshold for B cell activation. It binds the complement component fragments iC3b, C3D, and C3d. Also, this protein has a function in the complement system through serving as the cellular receptor specific for ligands such as C3 and C4. Recombinant Human CD21, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

< 1 EU per 1ug of protein (determined by LAL method)

Human