Recombinant human DDIT-3/CHOP protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

GADD153, also known as DNA-damage-inducible transcript 3 (DDIT3), is a basic domain-leucine zipper (bZIP) transcription factor of C/EBP family. This protein has been shown to be up-regulated by several stresses, such as amino acid or glucose starvation, endoplasmic reticulum (ER) stress, osmotic stress and hypoxia. GADD153 protein may play a role in ER stress-mediated apoptosis and in disease including diabetes, brain ischemia and neurodegenerative disease. Recombinant GADD153 fused with His-tag, was expressed in E. coli and purified by conventional chromatography techniques.

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol

Cell Cycle

Human