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Recombinant human HIF-1 alpha/HIF1A protein

ArtNr NKM-HIF0501-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag Untagged
Purity > 90% by SDS-PAGE
Sequence MEFKLELVEK LFAEDTEAKN PFSTQDTDLD LEMLAPYIPM DDDFQLRSFD QLSPLESSSA SPESASPQST VTVFQQTQIQ EPTANATTTT ATTDELKTVT KDRMEDIKIL IASPSPTHIH KETTSATSSP YRDTQSRTAS PNRAGKGVIE QTEKSHPRSP NVLSVALSQR TTVPEEELNP KILALQNAQR KRKMEHDGSL FQAVGIGTLL QQPDDHAATT SLSWKRVKGC KS
Citations Okuyama H. et al., (2006) J. Biol Chem. 281(22):15554-63
Berra E. et al., (2006) EMBO.7(1):41-5

Hussain KK, et al. Amperometric sensing of HIF1α expressed in cancer cells and the effect of hypoxic mimicking agents. (Biosens Bioelectron. 2016){https://pubmed.ncbi.nlm.nih.gov/27132006/}
NCBI NP_001521
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Hypoxia inducible factor 1 subunit alpha,Hypoxia-inducible factor 1-alpha,HIF1-alpha,ARNT-interacting protein,Basic-helix-loop-helix-PAS protein MOP1,Class E basic helix-loop-helix protein 78,bHLHe78,Member of PAS protein 1,PAS domain-containing protein 8,PASD8,MOP1
Similar products HIF-1 alpha, HIF1A, MOP1, PASD8, bHLHe78, ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, Member of PAS protein 1, HIF1 alpha, ARNT interacting protein, Member of PAS superfamily 1, HIF 1alpha, HIF 1A, HIF1 A, Hypoxia inducible factor 1 alpha, Hypoxia inducible factor 1 alpha isoform I.3, Hypoxia inducible factor 1 alpha subunit, Hypoxia inducible factor 1 alpha subunit basic helix loop helix transcription factor, Member of the PAS Superfamily 1, MOP 1, PASD 8, HIF1 a, Hypoxia-inducible factor-1a, Hif-1 alpha (530-826 aa), Hypoxia-inducible factor 1 alpha, Hypoxia-inducible factor-1a Basic helix loop helix PAS protein MOP1, HIF0501-10ug, HIF0501-20ug, HIF0501-50ug, HIF0501-100ug, HIF0501-250ug, HIF0501-500ug, HIF0501-1mg, HIF0501-10, HIF0501-20, HIF0501-50, HIF0501-100, HIF0501-250, HIF0501-500, HIF0501-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
32.8 kDa (298aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Description
Hypoxia-inducible factor-1 (HIF-1), identified as one of the transcription factors, has been found to play an essential role in oxygen homeostasis. HIF-1 is a heterodimer composed of HIF-1beta subunit and one of three subunits (Hif-1alpha, Hif-2 or Hif-3). The activation of Hif-1 is closely associated with a variety of tumors and oncogenic pathways. Hif-1alpha consists of DNA binding domain (DBD domain), Dimerization domain and C-terminla regulatiory domains, including two transactivation domains (TAD), an oxygen-dependent degradation (ODD) domain, and inhibitory domains. Hif-1 alpha (530-826 residues) contains two TAD and inhibitory domain. Recombinant Hif-1 alpha (530-826 residues) was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Cell Cycle
Domain
530-826aa
Species of Protein
Human
Manufacturer - Search Terms
HIF1 a, Hypoxia-inducible factor-1a, HIF1A, MOP1, Hif-1 alpha (530-826 aa), HIF-1 alpha, HIF1 alpha, ARNT-interacting protein, Member of PAS protein 1, Basic-helix-loop-helix-PAS protein MOP1, Hypoxia-inducible factor 1 alpha, Hypoxia-inducible factor-1a Basic helix loop helix PAS protein MOP1, ARNT interacting protein, bHLHe78, HIF 1A, HIF 1alpha, HIF1 A, Hypoxia inducible factor 1 alpha, Hypoxia inducible factor 1 alpha isoform I.3, Hypoxia inducible factor 1 alpha subunit, Hypoxia inducible factor 1 alpha subunit basic helix loop helix transcription factor, Member of PAS protein 1, Member of PAS superfamily 1, Member of the PAS Superfamily 1, MOP 1, PASD 8, PASD8, HIF0501-10ug, HIF0501-20ug, HIF0501-50ug, HIF0501-100ug, HIF0501-250ug, HIF0501-500ug, HIF0501-1mg, HIF0501-10, HIF0501-20, HIF0501-50, HIF0501-100, HIF0501-250, HIF0501-500, HIF0501-1
Manufacturer - Alternative Names
Hypoxia inducible factor 1 subunit alpha, Hypoxia-inducible factor 1-alpha, HIF1-alpha, ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, Class E basic helix-loop-helix protein 78, bHLHe78, Member of PAS protein 1, PAS domain-containing protein 8, PASD8, MOP1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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