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Recombinant human Sirtulin 6/SIRT6 protein

ArtNr NKM-SIR0901-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MSVNYAAGLS PYADKGKCGL PEIFDPPEEL ERKVWELARL VWQSSSVVFH TGAGISTASG IPDFRGPHGV WTMEERGLAP KFDTTFESAR PTQTHMALVQ LERVGLLRFL VSQNVDGLHV RSGFPRDKLA ELHGNMFVEE CAKCKTQYVR DTVVGTMGLK ATGRLCTVAK ARGLRACRGE LRDTILDWED SLPDRDLALA DEASRNADLS
Citations Michishita E., et al. (2008) Nature. 452(7186):492-6.
Mostoslavsky R., et al. (2006) Cell. 124(2):315-29.
NCBI NP_057623
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias NAD-dependent protein deacylase sirtuin-6,Protein mono-ADP-ribosyltransferase sirtuin-6,Regulatory protein SIR2 homolog 6,SIR2-like protein 6,SIR2L6
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Manufacturer - Type
Proteins
Manufacturer - Category
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
41 kDa (375aa) confirmed by MALDI-TOF
Description
The SIRT6 is included in class IV of the sirtuin family, homologs to the yeast Sir2 protein. The functions of human sirtuins have not yet been determined; however, in yeast sirtuins are known to regulate epigenetic gene silencing. Also SIRT6, a chromatin-associated protein, appears to be involved in DNA repair. Recombinant SIRT6, fused to His-tag at N-terminus, was expressed in E. coli and purified by conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 20% glycerol, 1mM DTT, 0.1M NaCl, 0.1mM PMSF
Antigen Species
Human
Gene Category
Cell Cycle
Domain
1-355aa
Species of Protein
Human
Manufacturer - Search Terms
Mono-ADP-ribosyltransferase sirtuin-6, NAD-dependent protein deacylase sirtuin-6, Protein mono-ADP-ribosyltransferase sirtuin-6, Regulatory protein SIR2 homolog 6, SIR2 like protein 6, SIR2 related protein type 6, SIR2L6, SIR2-like protein 6, SIRT 6, SIRT6, Sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae), Sirtuin 6, Sirtuin 6 Mono ADP ribosyltransferase sirtuin 6, Sirtuin type 6, Sirtuin6, SIR0901-10ug, SIR0901-20ug, SIR0901-50ug, SIR0901-100ug, SIR0901-250ug, SIR0901-500ug, SIR0901-1mg, SIR0901-010, SIR0901-020, SIR0901-050, SIR0901-100, SIR0901-250, SIR0901-500, SIR0901-01M
Manufacturer - Similar Names
Mono-ADP-ribosyltransferase sirtuin-6, NAD-dependent protein deacylase sirtuin-6, Protein mono-ADP-ribosyltransferase sirtuin-6, Regulatory protein SIR2 homolog 6, SIR2 like protein 6, SIR2 related protein type 6, SIR2L6, SIR2-like protein 6, SIRT 6, SIRT6, Sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae), Sirtuin 6, Sirtuin 6 Mono ADP ribosyltransferase sirtuin 6, Sirtuin type 6, Sirtuin6, SIR0901-10ug, SIR0901-20ug, SIR0901-50ug, SIR0901-100ug, SIR0901-250ug, SIR0901-500ug, SIR0901-1mg, SIR0901-010, SIR0901-020, SIR0901-050, SIR0901-100, SIR0901-250, SIR0901-500, SIR0901-01M

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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