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Recombinant human beta-Synuclein protein

Recombinant human beta-Synuclein protein

ArtNr	NKM-SNB2001-100ug
Hersteller	NKMAX
Menge	100 ug
Quantity options	100 ug 20 ug 500 ug
Kategorie	Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Liquid
Applikationen	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Konjugat/Tag	Untagged
Purity	> 95% by SDS-PAGE
Sequence	MDVFMKGLSM AKEGVVAAAE KTKQGVTEAA EKTKEGVLYV GSKTREGVVQ GVASVAEKTK EQASHLGGAV FSGAGNIAAA TGLVKREEFP TDLKPEEVAQ EAAEEPLIEP LMEPEGESYE DPPQEEYQEY EPEA
Citations	Jakes R., et al. (1994) FEBS lett. 345, 27-32. Kim J.,et al. (1997) Molecules and Cells. 7, 78-83. Hashimoto M., et al. (2001) Neuron 32, 213-223. Ahn KJ, et al. Amino acid sequence motifs and mechanistic features of the membrane translocation of alpha-synuclein. (J Neurochem. 2006){https://pubmed.ncbi.nlm.nih.gov/16524375/} JY Park, et al. Microglial phagocytosis is enhanced by monomeric alpha-synuclein, not aggregated alpha-synuclein: implications for Parkinsons disease. (Glia. 2008){https://pubmed.ncbi.nlm.nih.gov/18449945/} Kim KS, et al. Regulation of Weibel-Palade body exocytosis by alpha-synuclein in endothelial cells. (J Biol Chem. 2010){https://pubmed.ncbi.nlm.nih.gov/20448034/} Kawakami F, et al. Stimulatory effect of α-synuclein on the tau-phosphorylation by GSK-3β. (FEBS J. 2011){https://pubmed.ncbi.nlm.nih.gov/21985244/} Konno M, et al. Suppression of dynamin GTPase decreases a-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy. (Mol Neurodegener. 2012){https://pubmed.ncbi.nlm.nih.gov/22892036/} Førland MG, et al. Validation of a new assay for α-synuclein detection in cerebrospinal fluid. (Clin Chem Lab Med. 2017){https://pubmed.ncbi.nlm.nih.gov/27474841/} Kobayashi J, et al. Extracellular α-synuclein enters dopaminergic cells by modulating flotillin-1-assisted dopamine transporter endocytosis. (FASEB J. 2019){https://pubmed.ncbi.nlm.nih.gov/31211923/}
NCBI	NP_001001502.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Beta-synuclein,SNCB beta-Synuclein,B-synuclein,Phosphoneuroprotein 14,PNP14,Synuclein beta
Similar products	Phosphoneuroprotein 14, Beta-synuclein, Synuclein beta, PNP14, Beta synuclein, beta synuclein, b-Synuclein, SNCB beta-Synuclein, B-synuclein, SNB2001-10ug, SNB2001-20ug, SNB2001-50ug, SNB2001-100ug, SNB2001-250ug, SNB2001-500ug, SNB2001-1mg, SNB2001-10, SNB2001-20, SNB2001-50, SNB2001-100, SNB2001-250, SNB2001-500, SNB2001-1
Lieferbar
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	14.2 kDa (134aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Description	beta-synuclein (amino acids 1-134), an acidic neuronal protein of 134 amino acids, is extremely heat-resistant. beta-synucelin also has a chaperone-like activity. Recently, beta-synuclein has been suggested to inhibit
Concentration	1mg/ml (determined by BCA assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 0.1 M NaCl, 1mM MgCl2
Antigen Species	Human
Gene Category	Neuroscience
Domain	1-134aa
Species of Protein	Human
Manufacturer - Search Terms	b-Synuclein, Beta-synuclein, SNCB beta-Synuclein, B-synuclein, Beta synuclein, beta synuclein, Phosphoneuroprotein 14, PNP14, Synuclein beta, SNB2001-10ug, SNB2001-20ug, SNB2001-50ug, SNB2001-100ug, SNB2001-250ug, SNB2001-500ug, SNB2001-1mg, SNB2001-10, SNB2001-20, SNB2001-50, SNB2001-100, SNB2001-250, SNB2001-500, SNB2001-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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NKM-SNB2001-100ug-datasheet.pdf

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Einfache Bestellung Periodische Bestellung

Menge: 100 ug

lieferbar

Lieferung vsl. bis 31.07.2025