Vergleich

Rabbit antibody to ABCG2

ArtNr OSA00214W
Hersteller Osenses
Menge 100ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Monkey (Cynomolgus, Simian)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias ATP-binding cassette sub-family G member 2, Breast cancer resistance protein, CDw338, Mitoxantrone resistance-associated protein, Placenta-specific ATP-binding cassette transporter, CD338, ABCP, BCRP, BCRP1, MXR
Similar products BCRP, ABCP, BCRP1, CD338, CDw338, MXR, Breast cancer resistance protein, Mitoxantrone resistance-associated protein, Placenta-specific ATP-binding cassette transporter, ATP-binding cassette sub-family G member 2
Lieferbar
Also known
ATP-binding cassette sub-family G member 2, Breast cancer resistance protein, CDw338, Mitoxantrone resistance-associated protein, Placenta-specific ATP-binding cassette transporter, CD338, ABCP, BCRP, BCRP1, MXR
Target
FUNCTION: Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
Subcellular location: Cell membrane; Multi-pass membrane protein
Tissue specificity: Highly expressed in placenta. Low expression in small intestine, liver and colon.
Spcs X-react.
Human, marmoset, rat, mouse. Other species not yet tested.
Applications info
IHC, WB. A dilution of 1 : 1000 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Zhou S, et al. Nat. Med. 7:1028-1034(2001)
Limitation
For research use only
Immunogen
A synthetic peptide from human ABCG1 conjugated to blue carrier protein was used as the antigen.
Conjugate
Unconjugated antibody
Accession
http://www.uniprot.org/uniprot/Q9UNQ0
http://www.uniprot.org/uniprot/F7B5F8
http://www.uniprot.org/uniprot/Q80W57
http://www.uniprot.org/uniprot/Q7TMS5
Purity
Whole serum
Clonality
Polyclonal
Specificity
Specific for ABCG2.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ul
Lieferbar: In stock
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