Vergleich

Rabbit antibody to Enolase

ArtNr OSN00063W
Hersteller Osenses
Menge 100ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Monkey (Cynomolgus, Simian)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Alpha-enolase, 2-phospho-D-glycerate hydro-lyase, Enolase 1, Non-neural enolase, NNE, Eno1<br/>Gamma enolase, 2-phospho-D-glycerate hydro-lyase, Enolase 2, Neural enolase, Neuron-specific enolase, ENOG, NSE, Eno2<br/>Beta-enolase, 2-phospho-D-glycerate hy
Similar products NSE, Neural enolase, Neuron-specific enolase, Enolase 2, NNE, Eno3, 2-phospho-D-glycerate hydro-lyase, MSE, Alpha-enolase, Enolase 1, Enolase 3, Non-neural enolase, Muscle-specific enolase, Skeletal muscle enolase, ENOG, Eno1
Gamma enolase, Eno2
Beta-enolase
Lieferbar
Also known
Alpha-enolase, 2-phospho-D-glycerate hydro-lyase, Enolase 1, Non-neural enolase, NNE, Eno1
Gamma enolase, 2-phospho-D-glycerate hydro-lyase, Enolase 2, Neural enolase, Neuron-specific enolase, ENOG, NSE, Eno2
Beta-enolase, 2-phospho-D-glycerate hydro-lyase, Enolase 3, Muscle-specific enolase, MSE, Skeletal muscle enolase, Eno3
Target
Function: Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.
Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific. ENO1 interacts with PLG in the neuronal plasma membrane and promotes its activation. The C-terminal lysine is required for this binding. In vitro, interacts with several glycolytic enzymes including PKM2, PGM, CKM and aldolase. Also binds troponin, in vitro.
Subcellular location: Cytoplasm. Cell membrane. Note: Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form. ENO1 is localized to the M-band.
Tissue specificity: The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. In striated muscle, expression of ENO1 appears to be independent of fiber type.
Spcs X-react.
Human, rat, mouse, marmoset. Other species not yet tested.
Applications info
WB. A dilution of 1 : 2000 to 1:6000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. McAleese S.M, et al. Eur. J. Biochem. 178:413-417(1988)
Limitation
For research use only
Immunogen
A synthetic peptide from internal region of human Enolase conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
Conjugate
Unconjugated antibody
Accession
http://www.uniprot.org/uniprot/P09104
http://www.uniprot.org/uniprot/P15429
http://www.uniprot.org/uniprot/P17182
Purity
Whole serum
Clonality
Polyclonal
Specificity
Specific for Enolase (alpha, beta, gamma).
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ul
Lieferbar: In stock
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