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Rabbit antibody to P2X1

Rabbit antibody to P2X1

ArtNr	OSP00029W
Hersteller	Osenses
Menge	100ul
Kategorie	Neuroscience Neural Lineage Markers Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Monkey (Cynomolgus, Simian)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	P2RX1, P2X1, P2X purinoceptor 1, ATP receptor
Similar products	P2RX1, ATP receptor, P2X1, P2X purinoceptor 1
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Also known	P2RX1, P2X1, P2X purinoceptor 1, ATP receptor
Target	FUNCTION: Ligand gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death. Subcellular location: Membrane; Multi-pass membrane protein. Involvement in disease: Defects in P2RX1 are a cause of bleeding disorder
Spcs X-react.	Mouse, human, rat, marmoset. Other species not yet tested.
Applications info	IHC, WB. A dilution of 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Shipping	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Valera S, et al. Recept. Channels 3:283-289(1995)
Limitation	For research use only
Immunogen	A synthetic peptide from the cytoplasmic domain of human P2X1 conjugated to blue carrier protein was used as the antigen. The antigen shares 92% identity with rat and mouse sequence.
Conjugate	Unconjugated antibody
Accession	http://www.uniprot.org/uniprot/P51575 http://www.uniprot.org/uniprot/P47824 http://www.uniprot.org/uniprot/P51576
Purity	Whole serum
Clonality	Polyclonal
Specificity	Specific for P2RX1.
Format	Lyophilised
Reconstitution	Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100ul

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