Comparison

Rabbit antibody to P2X1

Item no. OSP00029W
Manufacturer Osenses
Amount 100ul
Category
Type Antibody Polyclonal
Applications WB, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Monkey (Cynomolgus, Simian)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias P2RX1, P2X1, P2X purinoceptor 1, ATP receptor
Similar products P2RX1, ATP receptor, P2X1, P2X purinoceptor 1
Available
Also known
P2RX1, P2X1, P2X purinoceptor 1, ATP receptor
Target
FUNCTION: Ligand gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death.
Subcellular location: Membrane; Multi-pass membrane protein.
Involvement in disease: Defects in P2RX1 are a cause of bleeding disorder
Spcs X-react.
Mouse, human, rat, marmoset. Other species not yet tested.
Applications info
IHC, WB. A dilution of 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Valera S, et al. Recept. Channels 3:283-289(1995)
Limitation
For research use only
Immunogen
A synthetic peptide from the cytoplasmic domain of human P2X1 conjugated to blue carrier protein was used as the antigen. The antigen shares 92% identity with rat and mouse sequence.
Conjugate
Unconjugated antibody
Accession
http://www.uniprot.org/uniprot/P51575
http://www.uniprot.org/uniprot/P47824
http://www.uniprot.org/uniprot/P51576
Purity
Whole serum
Clonality
Polyclonal
Specificity
Specific for P2RX1.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ul
Available: In stock
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