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Rabbit antibody to ADAM22

Rabbit antibody to ADAM22

ArtNr	OSA00147W
Hersteller	Osenses
Menge	100ul
Kategorie	Neuroscience Neural Signaling Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Disintegrin and metalloproteinase domain-containing protein 22, Metalloproteinase disintegrin ADAM22-3, Metalloproteinase like, disintegrin like, and cysteine-rich protein 2, MDC2
Similar products	MDC2, and cysteine-rich protein 2, Metalloproteinase like, disintegrin like, Disintegrin and metalloproteinase domain-containing protein 22, Metalloproteinase disintegrin ADAM22-3
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Also known	Disintegrin and metalloproteinase domain-containing protein 22, Metalloproteinase disintegrin ADAM22-3, Metalloproteinase like, disintegrin like, and cysteine-rich protein 2, MDC2
Target	FUNCTION: Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation. Neuronal receptor for LGI1. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein TISSUE SPECIFICITY: Highly expressed in the brain and in some high-grade but not low-grade gliomas. Detected slightly or not at all in other tissues.
Spcs X-react.	Mouse, human. Other species not yet tested.
Applications info	IHC, WB (confirmed by recombinant protein). A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Shipping	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Sagane K, et al. Biochem. J. 334:93-98(1998) 2. Poindexter K, et al. Gene 237:61-70(1999)
Limitation	For research use only
Immunogen	A synthetic peptide from cytoplasmic domain of mouse ADAM22 (Metalloproteinase-disintegrin ADAM22-3) conjugated to an immunogenic carrier protein was used as the antigen.
Conjugate	Unconjugated antibody
Accession	http://www.uniprot.org/uniprot/Q9R1V6 http://www.uniprot.org/uniprot/Q9P0K1
Purity	Whole serum
Clonality	Polyclonal
Specificity	Specific for ADAM22.
Format	Lyophilised
Reconstitution	Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100ul

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