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Rabbit antibody to CRMP2 (500-550)

Rabbit antibody to CRMP2 (500-550)

ArtNr	OSC00047W
Hersteller	Osenses
Menge	100ul
Kategorie	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Dihydropyrimidinase-related protein 2, DRP-2, Collapsin response mediator protein 2, N2A3, DPYSL2, CRMP2
Similar products	DPYSL2, CRMP2, Dihydropyrimidinase-related protein 2, Collapsin response mediator protein 2, N2A3, DRP-2
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Also known	Dihydropyrimidinase-related protein 2, DRP-2, Collapsin response mediator protein 2, N2A3, DPYSL2, CRMP2
Target	FUNCTION: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration. SUBUNIT: Homotetramer, and heterotetramer with CRMP1, DPYSL3, DPYSL4 or DPYSL5. Interacts through its C-terminus with the C-terminus of CYFIP1/SRA1. Interacts with HTR4. SUBCELLULAR LOCATION: Cytoplasm. TISSUE SPECIFICITY: Ubiquitous.
Spcs X-react.	Human, mouse, rat. Other species not yet tested.
Applications info	IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Shipping	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Goshima Y, et al. Nature 376:509-514(1995). 2. Hamajima N, et al. Gene 180:157-163(1996).
Limitation	For research use only
Immunogen	A synthetic peptide from aa region 500-550 of human CRMP2 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat, mouse and chicken.
Conjugate	Unconjugated antibody
Accession	http://ca.expasy.org/uniprot/Q16555 http://ca.expasy.org/uniprot/P47942 http://ca.expasy.org/uniprot/O08553 http://ca.expasy.org/uniprot/Q90635
Purity	Whole serum
Clonality	Polyclonal
Specificity	Specific for CRMP2.
Format	Lyophilised
Reconstitution	Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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