Vergleich

Rabbit antibody to CHMP2A

ArtNr OSC00062W
Hersteller Osenses
Menge 100ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Chromatin-modifying protein 2a, Vacuolar protein-sorting-associated protein 2-1, Vps2-1, hVps2-1, Putative breast adenocarcinoma marker BC-2, BC2, Charged multivesicular body protein 2a
Similar products BC2, Charged multivesicular body protein 2a, Chromatin-modifying protein 2a, Putative breast adenocarcinoma marker BC-2, Vps2-1, hVps2-1, Vacuolar protein-sorting-associated protein 2-1
Lieferbar
Also known
Chromatin-modifying protein 2a, Vacuolar protein-sorting-associated protein 2-1, Vps2-1, hVps2-1, Putative breast adenocarcinoma marker BC-2, BC2, Charged multivesicular body protein 2a
Target
FUNCTION: Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. In case of infection, the HIV-1 virus takes advantage of the ESCRT-III complex for budding and exocytic cargos of viral proteins.
SUBCELLULAR LOCATION: Late endosome membrane; Peripheral membrane protein; Cytoplasmic side.
MISCELLANEOUS: Its overexpression strongly inhibits HIV-1 release.
Spcs X-react.
Mouse, rat, human. Other species not yet tested.
Applications info
IHC, WB. A dilution of 1 : 1000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Kemmer D, et al. BMC Genomics 7:48-48(2006).
Limitation
For research use only
Immunogen
A synthetic peptide from the n-terminal of human CHMP2A conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
Conjugate
Unconjugated antibody
Accession
http://ca.expasy.org/uniprot/O43633
http://ca.expasy.org/uniprot/B2RZB5
http://ca.expasy.org/uniprot/Q9DB34
Purity
Whole serum
Clonality
Polyclonal
Specificity
Specific for CHMP2A.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ul
Lieferbar: In stock
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