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Recombinant Human SOST protein (His tag)

ArtNr PDEH100206-20ug
Hersteller Elabscience
Menge 20 ug
Quantity options 100 ug 20 ug
Format Lyophilized Powder
Specific against Human (Homo sapiens)
Konjugat/Tag HIS
Purity > 95 % as determined by reducing SDS-PAGE.
Sequence Gln 24-Tyr 213
Alias CDD, DAND6, SOST1, VBCH
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Conjugate / Tag
N-His
Shipping Temperature
Biological Ice Packs
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Background
Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST is asecreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain. It shows sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. SOST is produced by the osteocyte and has anti-anabolic effects on bone formation. It is a negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
Reconstitution
Please refer to the printed manual for detailed information.
Formulation
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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