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BACE2 Antibody (Center) Blocking Peptide

BACE2 Antibody (Center) Blocking Peptide

ArtNr	ABC-BP6121a
Hersteller	Abcepta
Menge	500 ug
Kategorie	Neuroscience Aging & Neurological Disorders Peptides & Proteins Peptides
Typ	Peptides
Format	Lyophilized
Specific against	other
Citations	Clark, H.F., et al., Genome Res. 13(10):2265-2270 (2003).Basi, G., et al., J. Biol. Chem. 278(34):31512-31520 (2003).Barbiero, L., et al., Exp. Neurol. 182(2):335-345 (2003).Shi, X.P., et al., J. Biol. Chem. 278(23):21286-21294 (2003).Kondoh, K., et al., Breast Cancer Res. Treat. 78(1):37-44 (2003).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Beta-secretase 2,Aspartic-like protease 56 kDa,Aspartyl protease 1,ASP1,Asp 1,Beta-site amyloid precursor protein cleaving enzyme 2,Beta-site APP cleaving enzyme 2,Down region aspartic protease,DRAP,Memapsin-1,Membrane-associated aspartic protease 1,Theta-secretase,BACE2,AEPLC,ALP56,ASP21
Similar products	BACE2, AEPLC, ALP56, ASP21, Beta-secretase 2, Aspartic-like protease 56 kDa, Aspartyl protease 1, Beta-site amyloid precursor protein cleaving enzyme 2, Down region aspartic protease, Memapsin-1, Membrane-associated aspartic protease 1, Theta-secretase, ASP1, DRAP, Asp 1, Beta-site APP cleaving enzyme 2
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Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP6121a was selected from the Center region of human BACE2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by BACE2. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease.
Gene Name	BACE2
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

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ABC-BP6121a-datasheet.pdf

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Menge: 500 ug

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Lieferung vsl. bis 06.11.2025

Express-Lieferung: 13 Tage sparen

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