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BACE2 Antibody (Center) Blocking Peptide

BACE2 Antibody (Center) Blocking Peptide

Item no.	ABC-BP6121a
Manufacturer	Abcepta
Amount	500 ug
Category	Neuroscience Aging & Neurological Disorders Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Clark, H.F., et al., Genome Res. 13(10):2265-2270 (2003).Basi, G., et al., J. Biol. Chem. 278(34):31512-31520 (2003).Barbiero, L., et al., Exp. Neurol. 182(2):335-345 (2003).Shi, X.P., et al., J. Biol. Chem. 278(23):21286-21294 (2003).Kondoh, K., et al., Breast Cancer Res. Treat. 78(1):37-44 (2003).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Beta-secretase 2,Aspartic-like protease 56 kDa,Aspartyl protease 1,ASP1,Asp 1,Beta-site amyloid precursor protein cleaving enzyme 2,Beta-site APP cleaving enzyme 2,Down region aspartic protease,DRAP,Memapsin-1,Membrane-associated aspartic protease 1,Theta-secretase,BACE2,AEPLC,ALP56,ASP21
Similar products	BACE2, AEPLC, ALP56, ASP21, Beta-secretase 2, Aspartic-like protease 56 kDa, Aspartyl protease 1, Beta-site amyloid precursor protein cleaving enzyme 2, Down region aspartic protease, Memapsin-1, Membrane-associated aspartic protease 1, Theta-secretase, ASP1, DRAP, Asp 1, Beta-site APP cleaving enzyme 2
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP6121a was selected from the Center region of human BACE2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by BACE2. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease.
Gene Name	BACE2
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-BP6121a-datasheet.pdf

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Amount: 500 ug

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Delivery expected until 11/6/2025

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