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MAPK10 Antibody (N-term) Blocking Peptide

MAPK10 Antibody (N-term) Blocking Peptide

ArtNr	ABC-BP7222a
Hersteller	Abcepta
Menge	500 ug
Kategorie	Oncology Neuroscience Neural Signaling By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Peptides
Typ	Peptides
Format	Lyophilized
Specific against	other
Citations	Li, B.S., et al., EMBO J. 21(3):324-333 (2002).Yoshida, S., et al., J. Hum. Genet. 47(11):614-619 (2002).McDonald, P.H., et al., Science 290(5496):1574-1577 (2000).Yang, D.D., et al., Nature 389(6653):865-870 (1997).Gupta, S., et al., EMBO J. 15(11):2760-2770 (1996).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Mitogen-activated protein kinase 10,MAP kinase 10,MAPK 10,MAP kinase p49 3F12,Stress-activated protein kinase 1b,SAPK1b,Stress-activated protein kinase JNK3,c-Jun N-terminal kinase 3,MAPK10,JNK3,JNK3A,PRKM10,SAPK1B
Similar products	MAPK10, Mitogen-activated protein kinase 10, MAP kinase p49 3F12, Stress-activated protein kinase JNK3, c-Jun N-terminal kinase 3, JNK3, JNK3A, PRKM10, SAPK1B, Stress-activated protein kinase 1b, MAP kinase 10, MAPK 10, SAPK1b
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Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7222a was selected from the N-term region of human MAPK10. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	MAPK10 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kinase 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis.
Gene Name	MAPK10
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-BP7222a-datasheet.pdf

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Menge: 500 ug

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Lieferung vsl. bis 06.11.2025

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