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MAPK10 Antibody (N-term) Blocking Peptide

MAPK10 Antibody (N-term) Blocking Peptide

Item no.	ABC-BP7222a
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology Neuroscience Neural Signaling By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Li, B.S., et al., EMBO J. 21(3):324-333 (2002).Yoshida, S., et al., J. Hum. Genet. 47(11):614-619 (2002).McDonald, P.H., et al., Science 290(5496):1574-1577 (2000).Yang, D.D., et al., Nature 389(6653):865-870 (1997).Gupta, S., et al., EMBO J. 15(11):2760-2770 (1996).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Mitogen-activated protein kinase 10,MAP kinase 10,MAPK 10,MAP kinase p49 3F12,Stress-activated protein kinase 1b,SAPK1b,Stress-activated protein kinase JNK3,c-Jun N-terminal kinase 3,MAPK10,JNK3,JNK3A,PRKM10,SAPK1B
Similar products	MAPK10, Mitogen-activated protein kinase 10, MAP kinase p49 3F12, Stress-activated protein kinase JNK3, c-Jun N-terminal kinase 3, JNK3, JNK3A, PRKM10, SAPK1B, Stress-activated protein kinase 1b, MAP kinase 10, MAPK 10, SAPK1b
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7222a was selected from the N-term region of human MAPK10. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	MAPK10 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kinase 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis.
Gene Name	MAPK10
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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