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MEK4 (MAP2K4) Antibody (S257) Blocking peptide

MEK4 (MAP2K4) Antibody (S257) Blocking peptide

ArtNr	ABC-BP7916d
Hersteller	Abcepta
Menge	500 ug
Kategorie	Oncology By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Cell Biology Cell Status Senescence Peptides
Typ	Peptides
Format	Lyophilized
Specific against	other
Citations	Robinson,V.L.,Mol. Cancer Res. 6 (3), 501-508 (2008)Zhang,H.,J. Biol. Chem. 282 (20), 14788-14796 (2007)Salmeron,A.,EMBO J. 15 (4), 817-826 (1996)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Dual specificity mitogen-activated protein kinase kinase 4,MAP kinase kinase 4,MAPKK 4,JNK-activating kinase 1,MAPK/ERK kinase 4,MEK 4,SAPK/ERK kinase 1,SEK1,Stress-activated protein kinase kinase 1,SAPK kinase 1,SAPKK-1,SAPKK1,c-Jun N-terminal kinase kinase 1,JNKK,MAP2K4,JNKK1,MEK4,MKK4,PRKMK4,SEK1,SERK1,SKK1
Similar products	MAP2K4, SEK1, Dual specificity mitogen-activated protein kinase kinase 4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, MEK4, MKK4, JNKK, JNKK1, PRKMK4, SERK1, MAP kinase kinase 4, c-Jun N-terminal kinase kinase 1, MAPKK 4, MEK 4, Stress-activated protein kinase kinase 1, SAPK kinase 1, SAPKK-1, SAPKK1, SKK1
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Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7916d was selected from the S257 region of human MAP2K4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	MAP2K4 is a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. MAP2K4 is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.
Gene Name	MAP2K4
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-BP7916d-datasheet.pdf

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Menge: 500 ug

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Lieferung vsl. bis 06.11.2025

Express-Lieferung: 14 Tage sparen

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