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MEK4 (MAP2K4) Antibody (S257) Blocking peptide

MEK4 (MAP2K4) Antibody (S257) Blocking peptide

Item no.	ABC-BP7916d
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Cell Biology Cell Status Senescence Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Robinson,V.L.,Mol. Cancer Res. 6 (3), 501-508 (2008)Zhang,H.,J. Biol. Chem. 282 (20), 14788-14796 (2007)Salmeron,A.,EMBO J. 15 (4), 817-826 (1996)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Dual specificity mitogen-activated protein kinase kinase 4,MAP kinase kinase 4,MAPKK 4,JNK-activating kinase 1,MAPK/ERK kinase 4,MEK 4,SAPK/ERK kinase 1,SEK1,Stress-activated protein kinase kinase 1,SAPK kinase 1,SAPKK-1,SAPKK1,c-Jun N-terminal kinase kinase 1,JNKK,MAP2K4,JNKK1,MEK4,MKK4,PRKMK4,SEK1,SERK1,SKK1
Similar products	MAP2K4, SEK1, Dual specificity mitogen-activated protein kinase kinase 4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, MEK4, MKK4, JNKK, JNKK1, PRKMK4, SERK1, MAP kinase kinase 4, c-Jun N-terminal kinase kinase 1, MAPKK 4, MEK 4, Stress-activated protein kinase kinase 1, SAPK kinase 1, SAPKK-1, SAPKK1, SKK1
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7916d was selected from the S257 region of human MAP2K4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	MAP2K4 is a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. MAP2K4 is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.
Gene Name	MAP2K4
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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