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pro-NPY peptide (34-43), human - 0.1 mg

ArtNr AS-65602
Hersteller AnaSpec
Menge 0.1 mg
Kategorie
Typ Peptides
Format Lyophilized
Specific against other
Purity Peak Area by HPLC ≥95%
Sequence QXL®520-Arg-Gln-Arg-Tyr-Gly-Lys-Arg-Ser-Ser-Pro-Lys(5-FAM)-NH2
Citations 1. Elshabrawy HA, ET AL. Identification of a broad-spectrum antiviral small molecule against severe acute respiratory syndrome coronavirus and Ebola, Hendra, and Nipah viruses by using a novel high-throughput screening assay. J Virol. 2014;88(8):4353-4365. 2. Funkelstein L, et al. Cathepsin L participates in the production of neuropeptide Y in secretory vesicles, demonstrated by protease gene knockout and expression. J. Neurochem. 2008; 106:384-391.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias QXL520- RQRYGKRSSP- K(5-FAM)-NH2
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Catalog
Manufacturer - Applications
FRET; Protease activity; Screening; Receptor binding studies
Manufacturer - Category
Peptides
Manufacturer - Targets
pro-NPY
Manufacturer - Conjugate / Tag
FAM-QXL® 520
Shipping Temperature
RT
Storage Conditions
- 20 °C Protected from light
Molecular Weight
2211.3
Description
This peptide corresponds to host derived pro-NPY sequence with a cathepsin cleavage site. Host proteases, such as cathepsin L are involved in the processing and biosynthesis of neuropeptides including pro-NPY. In viral propagation, cathepsin mediated cleavage of viral proteins is necessary for cell entry, thereby affecting the host protein derived pro-NPY. The peptide is labeled with QXL520 and 5-FAM as FRET pair and thus can serve as a substrate for investigation enzyme cleavage. Neuropeptide Y (NPY) functions as a peptide neurotransmitter and as a neuroendocrine hormone. The active NPY peptide is generated in secretory vesicles by proteolytic processing of pro-NPY.
Product Group
LB1A1Z
Research Area
Immunology and Infectious disease; Cell Signaling / Lyophilized
Absorbtion (nm)
490
Emission (nm)
520
Sequence One-Letter Code
QXL®520- RQRYGKRSSP- K(5-FAM)-NH2
GTIN
5400535177416
Detection Method
Fluorescent
Usage
Research use
UNSPSC
12352202

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
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