« Back
Home /
pro-NPY peptide (34-43), human - 0.1 mg

pro-NPY peptide (34-43), human - 0.1 mg

Item no.	AS-65602
Manufacturer	AnaSpec
Amount	0.1 mg
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Purity	Peak Area by HPLC ≥95%
Sequence	QXL®520-Arg-Gln-Arg-Tyr-Gly-Lys-Arg-Ser-Ser-Pro-Lys(5-FAM)-NH2
Citations	1. Elshabrawy HA, ET AL. Identification of a broad-spectrum antiviral small molecule against severe acute respiratory syndrome coronavirus and Ebola, Hendra, and Nipah viruses by using a novel high-throughput screening assay. J Virol. 2014;88(8):4353-4365. 2. Funkelstein L, et al. Cathepsin L participates in the production of neuropeptide Y in secretory vesicles, demonstrated by protease gene knockout and expression. J. Neurochem. 2008; 106:384-391.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	QXL520- RQRYGKRSSP- K(5-FAM)-NH2
Shipping Condition	Room temperature
Available
Manufacturer - Type	Catalog
Manufacturer - Applications	FRET; Protease activity; Screening; Receptor binding studies
Manufacturer - Category	Peptides
Manufacturer - Targets	pro-NPY
Manufacturer - Conjugate / Tag	FAM-QXL® 520
Shipping Temperature	RT
Storage Conditions	- 20 °C Protected from light
Molecular Weight	2211.3
Description	This peptide corresponds to host derived pro-NPY sequence with a cathepsin cleavage site. Host proteases, such as cathepsin L are involved in the processing and biosynthesis of neuropeptides including pro-NPY. In viral propagation, cathepsin mediated cleavage of viral proteins is necessary for cell entry, thereby affecting the host protein derived pro-NPY. The peptide is labeled with QXL520 and 5-FAM as FRET pair and thus can serve as a substrate for investigation enzyme cleavage. Neuropeptide Y (NPY) functions as a peptide neurotransmitter and as a neuroendocrine hormone. The active NPY peptide is generated in secretory vesicles by proteolytic processing of pro-NPY.
Product Group	LB1A1Z
Research Area	Immunology and Infectious disease; Cell Signaling / Lyophilized
Absorbtion (nm)	490
Emission (nm)	520
Sequence One-Letter Code	QXL®520- RQRYGKRSSP- K(5-FAM)-NH2
GTIN	5400535177416
Detection Method	Fluorescent
Usage	Research use
UNSPSC	12352202

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

AS-65602-safety-datasheet.pdf