Orexin B (human) trifluoroacetate salt

Biochemical Reagents

< -15℃

Like orexin A, orexin B (OXB) is a hypothalamic neuropeptide regulating the feeding behavior. Central administration of OXB to rats stimulated food consumption in a similar manner to orexin A, but the effect did not last as long as that of orexin A. The affinity of orexin B for the OX1 receptor is significantly lower (IC5o = 240 nM) than that of orexin A. Binding affinities for the OX2 receptor are similar for orexin A and B (IC5o = 38 nM and 36 nM, respectively, for displacement of radiolabeled orexin A bound to the receptor).

Trifluoroacetate