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Human CCR8 Protein, Flag,His Tag&Twin-Streptavidin Tag (Detergent) Europäischer Partner

ArtNr CC8-H52D6-20ug
Hersteller ACROBiosystems
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag Unconjugated, Streptavidin, FLAG
Purity 90%
Dry ice Yes
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Versandbedingung Trockeneis
Lieferbar
Manufacturer - Category
Protein
Manufacturer - Conjugate / Tag
N-Flag & C-10xHis & C-Twin Strep, Unconjugated
Shipping Temperature
Dry ice
Storage Conditions
-70°C
Molecular Weight
62.0 kDa
Manufacturer - Format
Liquid
Description
Human CCR8 Protein, Flag, His Tag&Twin-Streptavidin Tag (CC8-H52D6) is expressed from human 293 cells (HEK293). It is a membrane protein, contains complete wild type 7-transmembrane domans (TMD) and extracellular doman (ECD).
Background
This entry represents CC chemokine receptor 8 (CCR8), which it is expressed predominantly in lymphoid tissues and has also been found in glomerular podocytes and human umbilical vein endothelial cells (HUVECs). CCR8 is associated with Th2 lymphocytes, which are critical for allergy, and has a role in lymphocyte activation, migration, proliferation and differentiation and in allergic diseases. CCR8 binds to CCL1 (also known as I-309) and to CCL16 (also known as liver expressed chemokine). It also exhibits a high affinity for three chemokines of viral origin: vMIP-I, vMIP-II and vMCC-I.
Molecule
CCR8
Exp Region
Asp 2 - Ser 345
Characteristics
This protein carries a Flag tag at the N-terminus, and a polyhistidine tag at the C-terminus, followed by a twin streptavidin tag. The protein has a calculated MW of 62.0 kDa.
Endotoxin
1.0 EU per μg
Buffer
50 mM HEPES, 150 mM NaCl, Buffer B, pH7.5
Stability
● The product MUST be stored at -70°C or lower upon receipt
● -70°C for 3 months under sterile conditions.
Protectant
glycerol

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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