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Recombinant human NOQ1 protein

ArtNr NKM-ATGP0392-50ug
Hersteller NKMAX
Menge 50 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MVGRRALIVL AHSERTSFNY AMKEAAAAAL KKKGWEVVES DLYAMNFNPI ISRKDITGKL KDPANFQYPA ESVLAYKEGH LSPDIVAEQK KLEAADLVIF QFPLQWFGVP AILKGWFERV FIGEFAYTYA AMYDKGPFRS KKAVLSITTG GSGSMYSLQG IHGDMNVILW PIQSGILHFC GFQVLEPQLT YSIGHTPADA RIQILEGWKK
Citations Jaiswal AK., et al. (1988) J Biol Chem. 263(27):13572-8.
Traver RD., et al. (1992) Cancer Res. 52(4):797-802.
NCBI NP_000894.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias NAD(P)H quinone dehydrogenase 1,NMOR1,DIA4,Diaphorase,NADH/NADPH,Cytochrome b-5 reductase,NAD(P)H dehydrogenase,Quinone 1,DHQU,QR1,Azoreductase,DT-diaphorase,DTD,Menadione reductase,NAD(P)H:quinone oxidoreductase 1,Phylloquinone reductase,Quinone reductase 1
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Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
33.0 kDa (294aa) confirmed by MALDI-TOF
Description
NQO1 is a member of the NAD (P) H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This protein apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. NQO1 functions as an important part of cellular antioxidant defense by detoxifying quinines thus preventing the formation of reactive oxygen species. Altered expression of NQO1 has been seen in many tumors and is also associated with Alzheimer's disease (AD). Recombinant NQO1 protein was expressed in E. coli and purified by using conventional chromatography techniques
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 1mM DTT
Antigen Species
Human
Gene Category
Redox Proteins
Domain
1-274aa
Manufacturer - Search Terms
NQO1, ATGP0392-10ug, ATGP0392-20ug, ATGP0392-50ug, ATGP0392-100ug, ATGP0392-250ug, ATGP0392-500ug, ATGP0392-1mg, ATGP0392-10, ATGP0392-20, ATGP0392-50, ATGP0392-100, ATGP0392-250, ATGP0392-500, ATGP0392-1
Manufacturer - Alternative Names
NAD(P)H quinone dehydrogenase 1, NMOR1, DIA4, Diaphorase, NADH/NADPH, Cytochrome b-5 reductase, NAD(P)H dehydrogenase, Quinone 1, DHQU, QR1, Azoreductase, DT-diaphorase, DTD, Menadione reductase, NAD(P)H:quinone oxidoreductase 1, Phylloquinone reductase, Quinone reductase 1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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