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Biotinylated Human STEAP1 Full Length Protein, Avitag™,Flag&His Tag (Detergent) Europäischer Partner

ArtNr ST1-H82D3-20ug
Hersteller ACROBiosystems
Menge 20 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag Biotin, FLAG, Avi
Purity 90%
Dry ice Yes
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Versandbedingung Trockeneis
Lieferbar
Manufacturer - Category
Protein
Manufacturer - Conjugate / Tag
N-Flag & C-10xHis & C-Avi, Biotin-labeled
Shipping Temperature
Dry ice
Storage Conditions
-70°C, avoid light
Molecular Weight
44.7 kDa
Manufacturer - Format
Liquid
Description
Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on the cell surface of several human cancers, making it a promising therapeutic target to manage these diseases. It shares sequence homology with three enzymes (STEAP2-STEAP4) that catalyze the NADPH-dependent reduction of iron(III). Taking into account its high specificity and overexpression in human cancers, STEAP1 is nowadays a promising candidate to be imposed as a therapeutic target.
Background
Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on the cell surface of several human cancers, making it a promising therapeutic target to manage these diseases. It shares sequence homology with three enzymes (STEAP2-STEAP4) that catalyze the NADPH-dependent reduction of iron(III). Taking into account its high specificity and overexpression in human cancers, STEAP1 is nowadays a promising candidate to be imposed as a therapeutic target.
Molecule
STEAP1
Exp Region
Glu 2 - Leu 339
Characteristics
This protein carries a Flag tag at the N-terminus, and a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 44.7 kDa. The protein migrates as 40-43 kDa and 65-70 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
50 mM HEPES, 150 mM NaCl, Buffer A, pH7.5
Stability
● The product MUST be stored at -70°C or lower upon receipt
● -70°C for 3 months under sterile conditions.
Protectant
glycerol

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
lieferbar

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