SNRPE, Recombinant, Human, aa1-92, His-Tag (Small nuclear ribonucleoprotein E)

Blue Ice

12, 9

Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.2M sodium chloride, 5mM DTT, 1mM EDTA, 30% glycerol.

SNRPE, also known as SME, aids in the cytoplasmic construction of the usnRNPs by binding to a conserved Sm site on usnRNA and forming a stable snRNP core complex. As a core protein to usnRNP, the SNRPE associates with the entire u family of snRNAs including u1-u6. SNRPE also interacts with DDX20 and Small nuclear ribonucleoprotein polypeptide F.

Source:
Recombinant protein corresponding to aa1-92 of human SNRPE, fused to His-tag at N-terminal expressed in E. coli.

Molecular Weight:
~12.9kD

AA Sequence:
MGSSHHHHHH SSGLVPRGSH MAYRGQGQKV QKVMVQPINL IFRYLQNRSR IQVWLYEQVN MRIEGCIIGF DEYMNLVLDD AEEIHSKTKS RKQLGRIMLK GDNITLLQSV SN

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.