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Recombinant Mouse VEGFR3/FLT4 Protein (His Tag)

Recombinant Mouse VEGFR3/FLT4 Protein (His Tag)

ArtNr	PKSM040596-1mg
Hersteller	Elabscience
Menge	1 mg
Quantity options	100 ug 50 ug 1 mg
Kategorie	Oncology By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines Adenocarcinoma By Organ Bladder Cancer
Typ	Proteins
Format	Lyophilized Powder
Applikationen	ELISA
Specific against	Mouse (Murine, Mus musculus)
Host	HEK293 cells
Konjugat/Tag	HIS
Purity	> 97 % as determined by reducing SDS-PAGE.
Sequence	Met 1-Glu 775
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	AI323512, Chy, Flt-4, VEGFR-3, VEGFR3
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Category	Recombinant Proteins / Cytokines
Manufacturer - Conjugate / Tag	C-His
Shipping Temperature	This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight	86.4 kDa
Observed Molecular Weight	95-105 kDa
Background	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). The VEGFR3 protein is expressed mainly on lymphatic vessels but it is also up-regulated in tumor angiogenesis. Mutations in VEGFR3 have been identified in patients with primary lymphoedema. The VEGF-C/VEGF-D/VEGFR3 signaling pathway may provide a target for antilymphangiogenic therapy in prostate cancer, breast cancer, gastric cancer, lung cancer, non-small cell lung cancer (NSCLC), and so on.
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution	Please refer to the printed manual for detailed information.
Formulation	Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Immobilized mouse VEGFR3-His at 10 μg/mL (100 μl/well) can bind mouse Fc-VEGFD, The EC50 of mouse Fc-VEGFD is 44 ng/mL.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

PKSM040596-1mg-datasheet.pdf

PKSM040596-1mg-safety-datasheet.pdf