Recombinant Mouse Carboxylesterase-2/CES2 Protein (His Tag)

Recombinant Proteins / Others

This product is provided as lyophilized powder which is shipped with ice packs.

60.4 kDa

Carboxylesterase 2 (CES2) is a member of the carboxylesterase family and belongs to the multigene family. Carboxylesterase 2 is responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and beroin. It also serves to hydrolyze long-chain fatty acid esters and thioesters. It is speculated that carboxylesterases may play a role in lipid metabolism and the blood-brain barrier system and together with isform 1, are a serine esterase involved in both drug metabolism and activation. Human carboxylesterase 2 is commonly expressed in tumor tissues and irinotecan, a topoisomerase I inhibitor commonly used in the treatment of many solid tumors.

Please refer to the printed manual for detailed information.

Measured by its ability to hydrolyze pnitrophenylacetate. The specific activity is > 90, 000 pmoles/min/μg.