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Recombinant Mouse Interleukin-6/IL-6 Protein

ArtNr PKSM041097-20ug
Hersteller Elabscience
Menge 20 ug
Quantity options 10 ug 50 ug 100 ug 20 ug
Format Lyophilized Powder
Applikationen Cell Culture
Specific against Mouse (Murine, Mus musculus)
Host E.coli
Konjugat/Tag HIS
Purity > 98 % as determined by reducing SDS-PAGE.
Sequence Phe25-Thr211
Alias BSF, Interleukin, Interleukin HP, IFNB, B-cell hybridoma growth factor, BSF2, CDF, HGF, HSF, IFNB2, IL 6, Interleukin HP-1, Interleukin-6, Il-6, Il6
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Category
Recombinant Proteins / Cytokines
Manufacturer - Conjugate / Tag
C-His
Shipping Temperature
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
22.7 kDa
Observed Molecular Weight
24 kDa
Background
Interleukin-6 (IL-6) is a pro-inflammatory cytokine that also has an important role in immunity. Mouse IL-6 appears to be directly involved in the responses that occur after infection and injury and may prove to be as important as IL-1 in regulating the acute phase response. Mouse IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages, and endothelial cells. It acts upon a variety of cells, including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. IL-6 has a wide variety of biological functions: it plays an essential role in the final differentiation of B-cells into Ig-secreting cells, it induces myeloma and plasmacytoma growth, nerve cells differentiation in hepatocytes, and acute phase reactants.
Abbreviation
Interleukin-6; IL-6
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method.
Reconstitution
Please refer to the printed manual for detailed information.
Formulation
Lyophilized from filtered solution of PBS, PH8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Activity
Measure by its ability to induce proliferation in 7TD1 cells. The ED50 for this effect is <0.01 ng/mL. The specific activity of recombinant mouse IL-6 is approximately >1x 108 IU/mg.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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