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Human Alpha-Synuclein (A53T) Pre-formed Fibrils Protein, Tag Free

Human Alpha-Synuclein (A53T) Pre-formed Fibrils Protein, Tag Free

ArtNr	ALN-H5114-100ug
Hersteller	ACROBiosystems
Menge	100 ug
Quantity options	100 ug 1 mg 500 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Host	E.coli
Konjugat/Tag	Unconjugated
Purity	90%
Dry ice	Yes
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Versandbedingung	Trockeneis
Lieferbar
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	Native, Unconjugated
Shipping Temperature	Dry ice
Storage Conditions	-70°C
Molecular Weight	14.5 kDa
Manufacturer - Format	Liquid
Description	Alpha-synuclein is a neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. It acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. Abnormalities in alpha-synuclein are implicated in the pathogenesis of Parkinson's disease (PD). Alpha-synuclein is present in Lewy-bodies, the neuropathological hallmark of PD, and the protein and its aggregation have been widely linked to neurotoxic pathways that ultimately lead to neurodegeneration.
Background	Alpha-synuclein is a neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. It acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. Abnormalities in alpha-synuclein are implicated in the pathogenesis of Parkinson's disease (PD). Alpha-synuclein is present in Lewy-bodies, the neuropathological hallmark of PD, and the protein and its aggregation have been widely linked to neurotoxic pathways that ultimately lead to neurodegeneration.
Molecule	Alpha-Synuclein
Exp Region	Met 1 - Ala 140
Characteristics	This protein carries no "tag". The protein has a calculated MW of 14.5 kDa.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	● The product should be stored at -70°C or room temperature for short storage. Do not store fibrils on ice or at 4°C ● The unsonicated fibril is validated to be stable after storage at -70°C for 1 year under sterile conditions ● The sonicated fibril should be stored at -70°C for not more than 8 weeks.
Protectant	trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ALN-H5114-100ug-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 19.02.2026

Express-Lieferung: 2 Tage sparen

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