Anti-FABP7 Antibody

ArtNr	BOS-A02646
Hersteller	Boster
Menge	0.1 mg
Quantity options	0.1 mg 100 ul 100 ul/vial
Kategorie	Neuroscience Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Neural Development Obesity Immunohistochemistry Western Blot ELISA Lipid & Fatty Acid Transport Immunostaining
Format	Liquid
Applikationen	WB, ELISA, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Alias	MRG,BLBP,FABPB,B-FABP,MRG,Fatty acid-binding protein,brain,Brain lipid-binding protein
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	FABP7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	14889 MW
Clonality	Polyclonal
Application Details	FABP7 antibody can be used for detection of FABP7 by Western blot at 0.5 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Gene Name	FABP7
Gene Full Name	Fatty acid binding protein 7, brain
Background	FABP7 was initially isolated from a human fetal brain cDNA library and whose mRNA was expressed in adult brain and muscle tissues at low levels. The protein encoded by this gene is a member of the fatty acid binding protein (FABPs) family, a group of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. FABP7 is a downstream gene of the Pax6 transcription factor and has been suggested to be essential for the maintenance of neuroepithelial cells during early cortical development. More recently, FABP7 was found to be frequently expressed in melanomas. Down-regulation of FABP7 through RNAi expression could reduce in vitro cell proliferation and Matrigel invasion, suggesting that FABP7 may be a potential target for the development of diagnostic and therapeutic tools.
Immunogen	FABP7 antibody was raised against a 17 amino acid synthetic peptide from near the center of human FABP7. The immunogen is located within the last 50 amino acids of FABP7.
Contents	FABP7 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification	FABP7 Antibody is affinity chromatography purified via peptide column.
Concentration	1 mg/mL
Manufacturer - Research Category	Homeostasis
Protein Name	Fatty acid binding protein 7, brain
Protein Function	B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers (By similarity).
Subcellular Localization	Cytoplasm.
Description	Boster Bio Anti-FABP7 Antibody (Catalog # A02646). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human.
Tissue Specificity	Expressed in brain and other neural tissues.
Predicted Reactivity	Bovine, Chicken, Rat, Mouse

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BOS-A02646-datasheet.pdf

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